2.1.1.213: tRNA (guanine10-N2)-dimethyltransferase

This is an abbreviated version!
For detailed information about tRNA (guanine10-N2)-dimethyltransferase, go to the full flat file.

Word Map on EC 2.1.1.213

2.1.1.213

carotenoid

dioxygenase

thiouridine

acyclic

thump

Reaction

2 S-adenosyl-L-methionine +

= 2 S-adenosyl-L-homocysteine +

Synonyms

EC 2.1.1.32, N(2),N(2)-dimethylguanosine tRNA methyltransferase, PAB1283, PabTrm-G10, PabTrm-m2 2G10 enzyme, Trm-G10, tRNA:m2(2)G10 methyltransferase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.213 tRNA (guanine10-N2)-dimethyltransferase

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Results	in table
321	AA Sequence
2	Cloned(Commentary)
1	Metals/Ions
1	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
3	Organism
1	pH Optimum
2	Purification (Commentary)
5	Reaction
3	Reference
5	Substrates and Products (Substrate)
1	Subunits
8	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
2	Temperature Stability [°C]

Reference

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Reference on EC 2.1.1.213 - tRNA (guanine10-N2)-dimethyltransferase

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659377

Armengaud, J.; Urbonavicius, J.; Fernandez, B.; Chaussinand, G.; Bujnicki, J.M.; Grosjean, H.

N2-Methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in archaea and eukaryota

J. Biol. Chem.

279

37142-37152

2004

Pyrococcus abyssi (Q9UY84)

15210688

675372

Urbonavicius, J.; Armengaud, J.; Grosjean, H.

Identity elements required for enzymatic formation of N2,N2-dimethylguanosine from N2-monomethylated derivative and its possible role in avoiding alternative conformations in archaeal tRNA

J. Mol. Biol.

357

387-399

2006

Pyrococcus abyssi

16434050

713139

Gabant, G.; Auxilien, S.; Tuszynska, I.; Locard, M.; Gajda, M.J.; Chaussinand, G.; Fernandez, B.; Dedieu, A.; Grosjean, H.; Golinelli-Pimpaneau, B.; Bujnicki, J.M.; Armengaud, J.

THUMP from archaeal tRNA:m22G10 methyltransferase, a genuine autonomously folding domain

Nucleic Acids Res.

2483-2494

2006

Pyrococcus abyssi

16687654