2.1.1.173: 23S rRNA (guanine2445-N2)-methyltransferase
This is an abbreviated version!
For detailed information about 23S rRNA (guanine2445-N2)-methyltransferase, go to the full flat file.
Word Map on EC 2.1.1.173
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2.1.1.173
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ether
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n-acetylmuramic
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rrnas
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plasmalogens
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6-phosphate
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coa
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murnac
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haemophilus
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renamed
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peptidoglycan
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citrate
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glucokinase
- 2.1.1.173
- ether
-
n-acetylmuramic
- rrnas
-
plasmalogens
-
6-phosphate
- coa
- murnac
-
haemophilus
-
renamed
- peptidoglycan
- citrate
- glucokinase
Reaction
Synonyms
23S RNA m(2)G2445 methyltransferase, EC 2.1.1.51, EC 2.1.1.52, m2G2445 methyltransferase, ribosomal large subunit methyltransferase, RlmKL, RlmL, Smu472, ycbY
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 2.1.1.173 - 23S rRNA (guanine2445-N2)-methyltransferase
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REACTION DIAGRAM
S-adenosyl-L-methionine + guanine2069 in 23S rRNA
S-adenosyl-L-homocysteine + N7-methylguanine2069 in 23S rRNA
S-adenosyl-L-methionine + guanine2445 in 23S rRNA
S-adenosyl-L-homocysteine + N2-methylguanine2445 in 23S rRNA
S-adenosyl-L-homocysteine + N7-methylguanine2069 in 23S rRNA
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S-adenosyl-L-methionine + guanine2069 in 23S rRNA
S-adenosyl-L-homocysteine + N7-methylguanine2069 in 23S rRNA
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S-adenosyl-L-homocysteine + N2-methylguanine2445 in 23S rRNA
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S-adenosyl-L-methionine + guanine2445 in 23S rRNA
S-adenosyl-L-homocysteine + N2-methylguanine2445 in 23S rRNA
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S-adenosyl-L-methionine + guanine2445 in 23S rRNA
S-adenosyl-L-homocysteine + N2-methylguanine2445 in 23S rRNA
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S-adenosyl-L-methionine + guanine2445 in 23S rRNA
S-adenosyl-L-homocysteine + N2-methylguanine2445 in 23S rRNA
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S-adenosyl-L-methionine + guanine2445 in 23S rRNA
S-adenosyl-L-homocysteine + N2-methylguanine2445 in 23S rRNA
N2-methylguanosine2445 of the 23S rRNA is located in a cluster of modified nucleotides concentrated at the peptidyl transferase center of the ribosome. It is likely that the G2445 modification is necessary for prevention of nonfunctional secondary or tertiary structure formation at the peptidyl transferase center
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S-adenosyl-L-methionine + guanine2445 in 23S rRNA
S-adenosyl-L-homocysteine + N2-methylguanine2445 in 23S rRNA
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Smu472 adds the m2G2445 modification
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the bifunctional methyltransferase YcbY, i.e. RlmKL, adds the m7G2069 and m2G2445 modifications in Escherichia coli 23S rRNA, recognition of dual rRNA targets by YcbY
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additional information
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the bifunctional methyltransferase YcbY, i.e. RlmKL, adds the m7G2069 and m2G2445 modifications in Escherichia coli 23S rRNA, recognition of dual rRNA targets by YcbY
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