2.1.1.145: trans-aconitate 3-methyltransferase

This is an abbreviated version!
For detailed information about trans-aconitate 3-methyltransferase, go to the full flat file.

Reaction

Synonyms

AGR110Wp, Tmt1 methyltransferase, trans-aconitate 3-methyltransferase, trans-aconitate methyltransferase

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.145 trans-aconitate 3-methyltransferase

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Results	in table
9	AA Sequence
1	CAS Registry Number
1	Expression
1	Inhibitors
11	KM Value [mM]
2	Localization
4	Natural Substrates/ Products (Substrates)
4	Organism
1	PDB ID
1	Reaction
1	Reaction Type
4	Reference
15	Substrates and Products (Substrate)
4	Synonyms
1	Systematic Name

Substrates Products

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Substrates Products on EC 2.1.1.145 - trans-aconitate 3-methyltransferase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

S-adenosyl-L-methionine + (2R,3R)/(2S,3S)-3-isopropylmalate

S-adenosyl-L-homocysteine + ?

Saccharomyces cerevisiae

-

poor substrate

658074

-

-

?

S-adenosyl-L-methionine + (2R,3S)-3-isopropylmalate

S-adenosyl-L-homocysteine + ?

Saccharomyces cerevisiae

-

-

658074

-

-

?

S-adenosyl-L-methionine + (2S,3R)-3-isopropylmalate

S-adenosyl-L-homocysteine + ?

Saccharomyces cerevisiae

-

-

658074

-

-

?

S-adenosyl-L-methionine + 2-(1-methylethylidine)succinate

S-adenosyl-L-homocysteine + ?

Saccharomyces cerevisiae

-

-

658074

-

-

?

S-adenosyl-L-methionine + 3-butylmalate

S-adenosyl-L-homocysteine + ?

Saccharomyces cerevisiae

-

-

658074

-

-

?

S-adenosyl-L-methionine + cis-aconitate

S-adenosyl-L-homocysteine + (Z)-2-(methoxycarbonylmethyl)butenedioate

Saccharomyces cerevisiae

-

-

288663

-

-

?

S-adenosyl-L-methionine + isopropylfumarate

S-adenosyl-L-homocysteine + ?

Saccharomyces cerevisiae

-

poor substrate

658074

-

-

?

S-adenosyl-L-methionine + isopropylmaleate

S-adenosyl-L-homocysteine + ?

Saccharomyces cerevisiae

-

-

658074

-

-

?

S-adenosyl-L-methionine + itaconate

S-adenosyl-L-homocysteine + ?

Saccharomyces cerevisiae

-

-

288663

-

-

?

S-adenosyl-L-methionine + trans-aconitate

S-adenosyl-L-homocysteine + (E)-2-(methoxycarbonylmethyl)butenedioate

2 entries

additional information

?

-

2 entries

S-adenosyl-L-methionine + trans-aconitate

S-adenosyl-L-homocysteine + (E)-2-(methoxycarbonylmethyl)butenedioate

Eremothecium gossypii

Q74ZT8

-

728010

-

-

?

S-adenosyl-L-methionine + trans-aconitate

S-adenosyl-L-homocysteine + (E)-2-(methoxycarbonylmethyl)butenedioate

Saccharomyces cerevisiae

-

-

288663, 288664, 658074

-

-

?

additional information

?

-

Saccharomyces cerevisiae

-

the enzyme may work in two different pathways in two different ways: for detoxification in the citric acid cycle and for a possibly novel biosynthetic branch reaction of the leucine biosynthetic pathway

658074

-

-

?

additional information

?

-

Saccharomyces cerevisiae

-

no activity as substrate: 2-isopropylmalate

658074

-

-

?