1.8.99.B1: protein-disulfide reductase (acceptor)
This is an abbreviated version!
For detailed information about protein-disulfide reductase (acceptor), go to the full flat file.
Reaction
Synonyms
AaPDO, ApPDO, disulfide bond-forming enzyme, glutaredoxin related protein, PDO, PfPDO, protein disulfide oxidoreductase, SSO0192, SSO10610, Sso1120, SsPDO
ECTree
Advanced search results
Engineering
Engineering on EC 1.8.99.B1 - protein-disulfide reductase (acceptor)
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
C148S
mutant enzyme exhibits a lower activity compared to wild-type enzyme
C146S
not active in the insulin reductase assay, oxidation of the dithiol peptide NRCSQGSCWN is reduced
C35S
active in the insulin reductase assay, oxidation of the dithiol peptide NRCSQGSCWN is comparable to wild-type enzyme
C35S/C146S
not active in the insulin reductase assay, no oxidation of the dithiol peptide NRCSQGSCWN
C155S/C158S
with insulin as substrate the enzyme is completely inactive
C173S/C178S
with insulin as substrate the enzyme shows lower activity than wild-type enzyme
C41S/C44S
with insulin as substrate the enzyme shows lower activity than wild-type enzyme
C155S/C158S
-
with insulin as substrate the enzyme is completely inactive
-
C173S/C178S
-
with insulin as substrate the enzyme shows lower activity than wild-type enzyme
-
C41S/C44S
-
with insulin as substrate the enzyme shows lower activity than wild-type enzyme
-