1.1.1.82: malate dehydrogenase (NADP+)

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For detailed information about malate dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

(S)-malate dehydrogenase, dehydrogenase, malate (nicotinamide adenine dinucleotide phosphate), L-malate:NAD oxidoreductase, malate NADP dehydrogenase, malic dehydrogenase (nicotinamide adenine dinucleotide phosphate), MDH, NADP malate dehydrogenase, NADP+-dependent malate dehydrogenase, NADP-dependent malate dehydrogenase, NADP-linked malate dehydrogenase, NADP-malate dehydrogenase, NADP-malic enzyme, NADP-MDH, NADP-MDH1, NADP-MDH2, NADPH-MDH

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.82 malate dehydrogenase (NADP+)

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Results	in table
49	Activating Compound
445	AA Sequence
1	Application
1	CAS Registry Number
12	Cloned(Commentary)
27	Cofactor
4	Crystallization (Commentary)
8	Expression
24	General Information
3	General Stability
30	Inhibitors
125	KM Value [mM]
39	Localization
3	Metals/Ions
41	Molecular Weight [Da]
41	Natural Substrates/ Products (Substrates)
116	Organism
1	Oxidation Stability
10	Pathway
5	PDB ID
13	pH Optimum
1	pH Range
1	pH Stability
1	Posttranslational Modification
38	Protein Variants
14	Purification (Commentary)
2	Reaction
3	Reaction Type
107	Reference
2	Renatured (Commentary)
43	Source Tissue
8	Specific Activity [micromol/min/mg]
1	Storage Stability
139	Substrates and Products (Substrate)
34	Subunits
100	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
2	Temperature Range [°C]
7	Temperature Stability [°C]
12	Turnover Number [1/s]

Application

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Application on EC 1.1.1.82 - malate dehydrogenase (NADP+)

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

agriculture

Mesembryanthemum crystallinum

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changes in malate concentration and activity of NADP-dependent malate dehydrogenase are the effect of Botrytis cinerea infection of C3 or CAM-performing Mesembryanthemum crystallinum plants. Biotic stress applied on C3 plants leads to increase in malate concentration during the night and in consequence lead to increase in malate day/night fluctuations in infected leaves on the 2nd day post infection. It corresponds with induction of an additional isoform of NADP-dependent malate dehydrogenase, NADP-ME3. On the contrary, CAM-performing plants exhibit a decrease in malate concentration and a decay in its diurnal fluctuations as a reaction to Botrytis cinerea infection. This correlates with significant decrease in activities of NADP-dependent malate dehydrogenase isoforms

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