1.1.1.178: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
This is an abbreviated version!
For detailed information about 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.178
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1.1.1.178
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l-3-hydroxyacyl-coa
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2-methyl-3-hydroxybutyric
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hyperinsulinism
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tiglylglycine
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hydroxyacyl-coas
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choreoathetosis
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medicine
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lchad
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kcnj11
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2-methylacetoacetate
- 1.1.1.178
- l-3-hydroxyacyl-coa
-
2-methyl-3-hydroxybutyric
- hyperinsulinism
-
tiglylglycine
-
hydroxyacyl-coas
-
choreoathetosis
- medicine
- lchad
-
kcnj11
- 2-methylacetoacetate
Reaction
Synonyms
17beta-HSD10, 17beta-hydroxysteroid dehydrogenase type 10, 2-methyl-3-hydroxy-butyryl CoA dehydrogenase, 2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase, 2-methyl-3-hydroxybutyryl-CoA dehydrogenase, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase type II, dehydrogenase, 2-methyl-3-hydroxybutyryl coenzyme A, HADII, HSD10, MHBD, SCHAD, short chain 3-hydroxyacyl-CoA dehydrogenase, short-chain L-3-hydroxy-2-methylacyl-CoA dehydrogenase, type II 3-hydroxyacyl-CoA dehydrogenase
ECTree
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Inhibitors
Inhibitors on EC 1.1.1.178 - 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
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1-azepan-1-yl-2-phenyl-2-(4-thioxo-1,4-dihydro-pyrazolo[3,4-d]pyrimidin-5-yl)-ethanone
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specific inhibitor of SCHAD, forms a covalent adduct with NAD+ by a catalytic suicide mechanism