Sequence of C1S_RAT
EC Number:3.4.21.42
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Cleavage of Arg-/-Ala bond in complement component C4 to form C4a and C4b, and Lys(or Arg)-/-Lys bond in complement component C2 to form C2a and C2b: the "classical" pathway C3 convertase
Other sequences found for EC No. 3.4.21.42
General information:
Sequence
0 MWCFVFFSLL ASFSAEPTMY GEILSPNYPQ AYPNEVVKTW DIEVPEGFGI HLYFTHLDME
60 LSENCAYDSV QIISGGIEEE RLCGQRTSKS PNSPTVEEFQ FPYNRLQVVF TSDFSNEERF
120 TGFAAYYSAV DVNECTDFTD VPCSHFCNNF IGGYFCSCPP EYFLHDDMRT CGVNCSGDVF
180 TALIGEIASP NYPNPYPENS RCEYQIRLQE GFRLVLTIRR EDFDVEPADS EGNCHDSLTF
240 AAKNQQFGPY CGNGFPGPLT IKTQSNTLDI VFQTDLTGQN KGWKLRYHGD PIPCPKEISA
300 NSIWEPEKAK YVFKDVVKIT CVDGFEVVEG NVGSTSFYST CQSNGQWSNS RLECQPVDCG
360 VPEPIENGKV EDPEDTVFGS VIHYTCEEPY YYMEQEEGGE YHCAANGSWV NDQLGVELPK
420 CIPVCGVPTE PFKVQQRIFG GYSTKIQSFP WQVYFESPRG GGALIDEYWV LTAAHVVEGN
480 SDPVMYVGST LLKIERLRNA QRLITERVII HPSWKQEDDL NTRTNFDNDI ALVQLKDPVK
540 MGPTVAPICL PETSSDYNPS EGDLGLISGW GRTENRTNVI QLRGAKLPIT SLEKCQQVKV
600 ENPKARSNDY VFTDNMICAG EKGVDSCEGD SGGAFALPVP NVKDPKFYVA GLVSWGKKCG
660 TYGIYTKVKN YVDWILKTMQ ENSGPKKD
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
12135
Sakai H.,Nakashima S.,Yoshimura S.,Nishimura Y.,Sakai N.,Nozawa Y.
Molecular cloning of a cDNA encoding a serine protease homologous to complement Cls precursor from rat C6 glial cells and its expression during glial differentiation.
Gene
209
87-94
1998
12136
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
