EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.22.52 | Stroke |
18396356 |
Design and synthesis of calpain inhibitory 6-pyridone 2-carboxamide derivatives. |
causal interaction
therapeutic application
unassigned |
2
4
0 |
| 3.4.22.52 | Stroke |
19041242 |
Design and synthesis of 4-aryl-4-oxobutanoic acid amides as calpain inhibitors. |
causal interaction
therapeutic application
unassigned |
2
4
0 |
| 3.4.22.52 | Stroke |
29249590 |
Neuroprotective Effects of Oxytocin Hormone after an Experimental Stroke Model and the Possible Role of Calpain-1. |
ongoing research
therapeutic application
unassigned |
4
3
0 |
| 3.4.22.52 | Synovitis |
34006144 |
Intracellular versus extracellular inhibition of calpain I causes differential effects on pain in a rat model of joint inflammation. |
ongoing research
unassigned |
4
0 |
| 3.4.22.52 | Synucleinopathies |
12887682 |
Distinct cleavage patterns of normal and pathologic forms of alpha-synuclein by calpain I in vitro. |
unassigned |
0 |
| 3.4.22.52 | Synucleinopathies |
17456777 |
Calpain-cleavage of alpha-synuclein: connecting proteolytic processing to disease-linked aggregation. |
causal interaction
unassigned |
2
0 |
| 3.4.22.52 | Tauopathies |
29126071 |
?-Lipoic acid improves abnormal behavior by mitigation of oxidative stress, inflammation, ferroptosis, and tauopathy in P301S Tau transgenic mice. |
causal interaction
unassigned |
3
0 |
| 3.4.22.52 | Triple Negative Breast Neoplasms |
28089626 |
Cisplatin Induces Apoptosis Through the Endoplasmic Reticulum-mediated, Calpain 1 Pathway in Triple-negative Breast Cancer Cells. |
therapeutic application
unassigned |
1
0 |
| 3.4.22.52 | Triple Negative Breast Neoplasms |
28536704 |
Calpain-1 Expression in Triple-Negative Breast Cancer: A Potential Prognostic Factor Independent of the Proliferative/Apoptotic Index. |
causal interaction
diagnostic usage
unassigned |
4
4
0 |
| 3.4.22.52 | Triple Negative Breast Neoplasms |
32825941 |
The expression of calpain-1 and androgen receptor in breast cancer and their correlation with clinicopathological characteristics: An immunohistochemical retrospective study. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
4 |
