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<< < Results 11 - 20 of 436 > >>
EC Number
Disease
PubMed ID
Title of Publication
Category
Confidence Level
Alzheimer Disease
Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease.
causal interaction
ongoing research
unassigned
3
1
0
Alzheimer Disease
The calpain family and human disease.
causal interaction
diagnostic usage
unassigned
4
1
0
Alzheimer Disease
Calpain activation in neurodegenerative diseases: confocal immunofluorescence study with antibodies specifically recognizing the active form of calpain 2.
causal interaction
diagnostic usage
ongoing research
therapeutic application
3
1
2
2
Alzheimer Disease
Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain.
unassigned
0
Alzheimer Disease
The crystal structures of human calpains 1 and 9 imply diverse mechanisms of action and auto-inhibition.
causal interaction
ongoing research
unassigned
1
3
0
Alzheimer Disease
Design and synthesis of calpain inhibitory 6-pyridone 2-carboxamide derivatives.
causal interaction
therapeutic application
unassigned
2
4
0
Alzheimer Disease
Design and synthesis of 4-aryl-4-oxobutanoic acid amides as calpain inhibitors.
causal interaction
therapeutic application
unassigned
2
4
0
Alzheimer Disease
Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors.
unassigned
0
Alzheimer Disease
Accumulation of ?-synuclein in dementia with Lewy bodies is associated with decline in the ?-synuclein-degrading enzymes kallikrein-6 and calpain-1.
diagnostic usage
ongoing research
unassigned
3
1
0
Alzheimer Disease
Truncation and activation of GSK-3? by calpain I: a molecular mechanism links to tau hyperphosphorylation in Alzheimer's disease.
causal interaction
unassigned
3
0
<< < Results 11 - 20 of 436 > >>