EC Number   |
Substrates   |
Products   |
Reversibility   |
|---|
1.1.99.B12 | (R)-littorine + acceptor |
expression in yeast confirms that CYP80F1 catalyzes the oxidation of (R)-littorine with rearrangement to form hyoscyamine aldehyde, a putative precursor to hyoscyamine, and without rearrangement to form 3'-hydroxylittorine |
3'-hydroxylittorine + reduced acceptor |
- |
? |
1.1.99.B12 | (R)-littorine + acceptor |
expression in yeast confirms that CYP80F1 catalyzes the oxidation of (R)-littorine with rearrangement to form hyoscyamine aldehyde, a putative precursor to hyoscyamine, and without rearrangement to form 3'-hydroxylittorine |
hyoscyamine aldehyde + reduced acceptor |
- |
? |
1.1.99.B12 | (S)-littorine + acceptor |
products are (2'S,3'S)-3'-hydroxylittorine, and a minor amount of (2'S,3'R)-3'-hydroxylittorine |
(2'S,3'S)-3'-hydroxylittorine + (2'S,3'R)-3'-hydroxylittorine + ? |
- |
? |