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<< < Results 51 - 54 of 54
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B50ubiquitin-7-amido-4-trifluoromethylcoumarin + H2O the enzyme catalyzes proteolytic processing of the viral polyprotein and also shows significant in vitro deubiquitinating and de-ISGylating activities. The enzyme binds ubiquitin, the ubiquitin core makes mostly hydrophilic interactions with the enzyme, while the Leu-Arg-Gly-Gly C-terminus of ubiquitin is located in the catalytic cleft of the enzyme. The ubiquitin core binds to the palm, thumb and fingers domains of the enzyme, while its final four C-terminal residues bind into a narrow channel by a network of hydrogen bonds and reach towards the active site Severe acute respiratory syndrome-related coronavirus ubiquitin + 7-amino-4-trifluoromethylcoumarin - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B50VAKQGAGFKRTY + H2O - Human coronavirus NL63 VAKQGA + GFKRTY - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B50Z-KKAG-7-amido-4-methylcoumarin + H2O the catalytic efficiency toward Z-KKAG-7-amido-4-methylcoumarin is 5times higher than that for Z-LRGG-7-amido-4-methylcoumarin infectious bronchitis virus Z-KKAG + 7-amino-4-methylcoumarin - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B50Z-LRGG-7-amido-4-methylcoumarin + H2O - infectious bronchitis virus Z-LRGG + 7-amino-4-methylcoumarin - ?
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