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EC Number
Substrates
Commentary Substrates
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Commentary (Products)
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3.4.22.B50
polyubiquitin + H2O
the enzyme cleaves Lys48- and Lys63-linked polyubiquitin to monoubiquitin but not linear polyubiquitin
infectious bronchitis virus
monoubiquitin + ?
-
?
3.4.22.B50
ubiquitin + H2O
the enzyme cleaves the LRGG tail of ubiquitin
Human coronavirus NL63
?
-
?
3.4.22.B50
more
the enzyme is one of three distinct viral proteases (PLP1, PLP2 and 3CLpro) involved in processing of the replicase polyprotein
Murine coronavirus
?
-
?
3.4.22.B50
ubiquitin + H2O
the enzyme processes both K-48 and K-63 linked polyubiquitin chains
porcine epidemic diarrhea virus
?
-
?
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