EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
adrenal cortex |
both 15-hydroxyprostaglandin dehydrogenase mRNA and protein levels are significantly higher in kidney cortex than in papilla. Enzyme is mainly localized to the tubular epithelial cells in kidney cortex and outer medulla |
684372 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
adrenal cortex |
- |
668413 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
adrenal cortex |
isozyme type 2 |
656091 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
adrenal cortex |
- |
-, 668428 |
1.1.1.197 | 15-hydroxyprostaglandin dehydrogenase (NADP+) |
adrenal cortex |
- |
347830 |
1.1.1.38 | malate dehydrogenase (oxaloacetate-decarboxylating) |
adrenal cortex |
- |
286698 |
1.1.1.49 | glucose-6-phosphate dehydrogenase (NADP+) |
adrenal cortex |
- |
286980 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
adrenal cortex |
- |
656654 |
1.14.14.16 | steroid 21-monooxygenase |
adrenal cortex |
- |
285446, 673924, 734302, 735122 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
adrenal cortex |
constitutive expression of HO-2 |
688006 |
1.14.14.19 | steroid 17alpha-monooxygenase |
adrenal cortex |
- |
692540, 726923, 727701, 727953 |
1.14.14.32 | 17alpha-hydroxyprogesterone deacetylase |
adrenal cortex |
- |
706819, 728827 |
1.14.14.32 | 17alpha-hydroxyprogesterone deacetylase |
adrenal cortex |
zona fasciculata, zona reticularis |
665842 |
1.14.15.4 | steroid 11beta-monooxygenase |
adrenal cortex |
- |
285387, 285389, 285390, 285391, 285393, 285394, 285395, 285396, 285398, 285399, 285400, 285401, 285402, 285403, 285404, 285405, 285410, 285411, 673345, 724701 |
1.14.15.4 | steroid 11beta-monooxygenase |
adrenal cortex |
capsular portion in zona glomerulosa cells, decapsular in zonae fasciculata and reticularis |
285392, 285397 |
1.14.15.5 | corticosterone 18-monooxygenase |
adrenal cortex |
- |
438757 |
1.14.15.6 | cholesterol monooxygenase (side-chain-cleaving) |
adrenal cortex |
- |
285412, 285413, 285414, 285415, 285416, 285417, 285418, 285419, 285420, 285421, 285424, 285425, 285426, 285427, 285428, 285429, 285430, 285431, 285432, 285433, 658811, 703418, 703625, 703876, 704039 |
1.18.1.6 | adrenodoxin-NADP+ reductase |
adrenal cortex |
- |
718572, 718822, 719028, 719386, 719389, 719398, 719475, 719482, 719751, 719752, 719768, 719769 |
1.4.3.4 | monoamine oxidase |
adrenal cortex |
of adrenal gland |
655721 |
1.5.1.15 | methylenetetrahydrofolate dehydrogenase (NAD+) |
adrenal cortex |
- |
-, 392084, 392085 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
adrenal cortex |
Northern blot analysis of human tissues |
659136 |
2.7.11.11 | cAMP-dependent protein kinase |
adrenal cortex |
- |
662180 |
2.7.11.12 | cGMP-dependent protein kinase |
adrenal cortex |
- |
760323 |
2.8.2.14 | bile-salt sulfotransferase |
adrenal cortex |
- |
676007 |
2.8.2.15 | steroid sulfotransferase |
adrenal cortex |
- |
645723, 645739 |
2.8.2.4 | estrone sulfotransferase |
adrenal cortex |
- |
760317 |
3.1.1.13 | sterol esterase |
adrenal cortex |
- |
133854 |
3.1.3.16 | protein-serine/threonine phosphatase |
adrenal cortex |
- |
134673 |
3.1.3.2 | acid phosphatase |
adrenal cortex |
sinusoidal cells |
666100 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
adrenal cortex |
PDE2 |
668987 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
adrenal cortex |
- |
686518 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
adrenal cortex |
of newborn mice |
686518 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
adrenal cortex |
tumor tissues from patients with isolated micronodular adrenocortical disease and no mutations in the coding PDE8B sequence or any other related genes (PRKAR1A, PDE11A) show downregulated PDE8B expression compared to normal adrenal cortex. PDE8B is a PDE gene linked to isolated micronodular adrenocortical disease. It is a candidate causative gene for other adrenocortical lesions linked to the cAMP signaling pathway and possibly for tumors in other tissues |
686518 |
3.13.2.1 | adenosylhomocysteinase |
adrenal cortex |
- |
137130 |
3.4.11.7 | glutamyl aminopeptidase |
adrenal cortex |
- |
36025 |
3.4.21.B26 | proprotein convertase 5 |
adrenal cortex |
- |
673910, 718009 |
3.4.21.B26 | proprotein convertase 5 |
adrenal cortex |
richest source of PC5A |
675967 |
3.4.23.5 | cathepsin D |
adrenal cortex |
- |
36935 |
3.4.23.B24 | signal peptide peptidase |
adrenal cortex |
- |
752819 |
3.4.24.64 | mitochondrial processing peptidase |
adrenal cortex |
- |
31387 |
3.4.24.71 | endothelin-converting enzyme 1 |
adrenal cortex |
- |
31470 |
3.5.1.23 | ceramidase |
adrenal cortex |
- |
720471 |
4.2.1.11 | phosphopyruvate hydratase |
adrenal cortex |
- |
665841 |
4.3.1.3 | histidine ammonia-lyase |
adrenal cortex |
- |
34308 |
4.3.2.9 | gamma-glutamylcyclotransferase |
adrenal cortex |
moderate expression |
720332 |
4.6.1.2 | guanylate cyclase |
adrenal cortex |
- |
34865 |
5.3.3.1 | steroid DELTA-isomerase |
adrenal cortex |
- |
721693 |
6.3.5.4 | asparagine synthase (glutamine-hydrolysing) |
adrenal cortex |
- |
745756 |