Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Source Tissue

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search
Show additional data
do not include text mining results
include AMENDA results (Automatic Mining of Enzyme Data)

Search term: C127I cell

Results 1 - 2 of 2
EC Number Recommended Name Source Tissue Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.2DNA topoisomerase (ATP-hydrolysing) C127I cell - 716400
Show all pathways known for 6.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.1acetate-CoA ligase C127I cell cells express higher levels of cytosolic acetyl-CoA synthetase ACSS2 under hypoxia than normoxia. Knockdown of ACSS2 by RNA interference in tumor cells enhances tumor cell death under long-term hypoxia in vitro. The ACSS2 suppression slows tumor growth in vivo. Tumor cells excrete acetate and the quantity increases under hypoxia, the pattern of acetate excretion follows the expression pattern of ACSS2. The ACSS2 knockdown leads to a corresponding reduction in the acetate excretion in tumor cells 703038
Results 1 - 2 of 2