EC Number |
Reaction |
Reference |
---|
3.4.19.12 | Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal) |
a 76-residue protein attached to proteins as an intracellular targeting signal |
- |
3.4.19.12 | Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal) |
Cys90 and His161 are involved in catalytic rate enhancement |
36456 |
3.4.19.12 | Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal) |
UCH-L1 is a neuro-specific multifunctional enzyme, deubiquinating, ubiquitinyl ligase, and also stabilizing ubiquitin monomers, C90 is the active site residue |
663891 |