3.4.1.1 leucine aminopeptidase transferred to EC 3.4.11.1 3.4.1.2 aminopeptidase transferred to EC 3.4.11.2 3.4.1.3 aminotripeptidase transferred to EC 3.4.11.4 3.4.1.4 proline iminopeptidase transferred to EC 3.4.11.5 3.4.11.1 leucyl aminopeptidase - 3.4.11.10 bacterial leucyl aminopeptidase - 3.4.11.11 aminopeptidase deleted 3.4.11.12 thermophilic aminopeptidase deleted 3.4.11.13 Clostridial aminopeptidase - 3.4.11.14 cytosol alanyl aminopeptidase - 3.4.11.15 aminopeptidase Y - 3.4.11.16 Xaa-Trp aminopeptidase - 3.4.11.17 tryptophanyl aminopeptidase - 3.4.11.18 methionyl aminopeptidase - 3.4.11.19 D-stereospecific aminopeptidase - 3.4.11.2 membrane alanyl aminopeptidase - 3.4.11.20 aminopeptidase Ey - 3.4.11.21 aspartyl aminopeptidase - 3.4.11.22 aminopeptidase I - 3.4.11.23 PepB aminopeptidase - 3.4.11.24 aminopeptidase S - 3.4.11.25 beta-peptidyl aminopeptidase - 3.4.11.26 intermediate cleaving peptidase 55 - 3.4.11.3 cystinyl aminopeptidase - 3.4.11.4 tripeptide aminopeptidase - 3.4.11.5 prolyl aminopeptidase - 3.4.11.6 aminopeptidase B - 3.4.11.7 glutamyl aminopeptidase - 3.4.11.8 pyroglutamyl aminopeptidase transferred to EC 3.4.19.3 3.4.11.9 Xaa-Pro aminopeptidase - 3.4.11.B3 Sulfolobus solfataricus aminopeptidase preliminary BRENDA-supplied EC number 3.4.11.B4 Pyrococcus horikoshii deblocking aminopeptidase preliminary BRENDA-supplied EC number 3.4.11.B5 Thermococcus onnurineus deblocking aminopeptidase preliminary BRENDA-supplied EC number 3.4.11.B6 Thermococcus kodakarensis deblocking aminopeptidase preliminary BRENDA-supplied EC number 3.4.11.B7 arginyl aminopeptidase PH1704 preliminary BRENDA-supplied EC number 3.4.11.B8 aminopeptidase TET1 preliminary BRENDA-supplied EC number 3.4.11.B9 TET2 peptidase preliminary BRENDA-supplied EC number 3.4.13.1 glycyl-glycine dipeptidase transferred to EC 3.4.13.18 3.4.13.10 beta-aspartyldipeptidase transferred to EC 3.4.19.5 3.4.13.11 dipeptidase transferred to EC 3.4.13.18, EC 3.4.13.19 3.4.13.12 Met-Xaa dipeptidase - 3.4.13.13 homocarnosinase transferred to EC 3.4.13.3 3.4.13.14 gamma-glutamyldipeptidase deleted 3.4.13.15 N2-beta-alanylarginine dipeptidase transferred to EC 3.4.13.18 3.4.13.16 aspartylphenylalanine dipeptidase deleted 3.4.13.17 non-stereospecific dipeptidase - 3.4.13.18 cytosol nonspecific dipeptidase - 3.4.13.19 membrane dipeptidase - 3.4.13.2 glycyl-leucine dipeptidase transferred to EC 3.4.13.18 3.4.13.20 beta-Ala-His dipeptidase - 3.4.13.21 dipeptidase E - 3.4.13.22 D-Ala-D-Ala dipeptidase - 3.4.13.23 cysteinylglycine-S-conjugate dipeptidase - 3.4.13.3 Xaa-His dipeptidase deleted, now covered by EC 3.4.13.18, cytosol nonspecific dipeptidase and EC 3.4.13.20, beta-Ala-His dipeptidase 3.4.13.4 Xaa-Arg dipeptidase - 3.4.13.5 Xaa-methyl-His dipeptidase - 3.4.13.6 Cys-Gly dipeptidase transferred to EC 3.4.11.6 3.4.13.7 Glu-Glu dipeptidase - 3.4.13.8 Pro-X dipeptidase transferred to EC 3.4.13.18 3.4.13.9 Xaa-Pro dipeptidase - 3.4.14.1 dipeptidyl-peptidase I - 3.4.14.10 tripeptidyl-peptidase II - 3.4.14.11 Xaa-Pro dipeptidyl-peptidase - 3.4.14.12 Xaa-Xaa-Pro tripeptidyl-peptidase - 3.4.14.13 gamma-D-glutamyl-L-lysine dipeptidyl-peptidase - 3.4.14.14 [mycofactocin precursor peptide] peptidase - 3.4.14.2 dipeptidyl-peptidase II - 3.4.14.3 acylamino-acid-releasing enzyme transferred to EC 3.4.19.1 3.4.14.4 dipeptidyl-peptidase III - 3.4.14.5 dipeptidyl-peptidase IV - 3.4.14.6 dipeptidyl-dipeptidase - 3.4.14.7 tetralysine endopeptidase deleted 3.4.14.8 tripeptidyl peptidase transferred to EC 3.4.14.9, EC 3.4.14.10 3.4.14.9 tripeptidyl-peptidase I - 3.4.15.1 peptidyl-dipeptidase A - 3.4.15.2 pepdidyl carboxyamidase transferred to EC 3.4.19.2 3.4.15.3 dipeptidyl carboxypeptidase transferred to EC 3.4.15.5 3.4.15.4 Peptidyl-dipeptidase B - 3.4.15.5 Peptidyl-dipeptidase Dcp - 3.4.15.6 cyanophycinase - 3.4.16.1 serine carboxypeptidase transferred to EC 3.4.16.5, EC 3.4.16.6 3.4.16.2 lysosomal Pro-Xaa carboxypeptidase - 3.4.16.3 tyrosine carboxypeptidase transferred to EC 3.4.16.5 3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase - 3.4.16.5 carboxypeptidase C - 3.4.16.6 carboxypeptidase D - 3.4.17.1 carboxypeptidase A - 3.4.17.10 carboxypeptidase E - 3.4.17.11 glutamate carboxypeptidase - 3.4.17.12 carboxypeptidase M - 3.4.17.13 Muramoyltetrapeptide carboxypeptidase - 3.4.17.14 Zinc D-Ala-D-Ala carboxypeptidase - 3.4.17.15 carboxypeptidase A2 - 3.4.17.16 membrane Pro-Xaa carboxypeptidase - 3.4.17.17 tubulinyl-Tyr carboxypeptidase - 3.4.17.18 carboxypeptidase T - 3.4.17.19 Carboxypeptidase Taq - 3.4.17.2 carboxypeptidase B - 3.4.17.20 Carboxypeptidase U - 3.4.17.21 Glutamate carboxypeptidase II - 3.4.17.22 metallocarboxypeptidase D - 3.4.17.23 angiotensin-converting enzyme 2 - 3.4.17.24 tubulin-glutamate carboxypeptidase - 3.4.17.25 glutathione-S-conjugate glycine hydrolase - 3.4.17.3 lysine carboxypeptidase - 3.4.17.4 Gly-Xaa carboxypeptidase - 3.4.17.5 aspartate carboxypeptidase deleted 3.4.17.6 alanine carboxypeptidase - 3.4.17.7 acylmuramoyl-alanine carboxypeptidase transferred to EC 3.4.19.10 3.4.17.8 muramoylpentapeptide carboxypeptidase - 3.4.17.9 carboxypeptidase S transferred to EC 3.4.17.4 3.4.17.B1 Sulfolobus solfataricus carboxypeptidase preliminary BRENDA-supplied EC number 3.4.17.B4 Thermococcus onnurineus carboxypeptidase preliminary BRENDA-supplied EC number 3.4.17.B5 Pyrococcus furiosus carboxypeptidase preliminary BRENDA-supplied EC number 3.4.18.1 cathepsin X - 3.4.19.1 acylaminoacyl-peptidase - 3.4.19.10 acylmuramoyl-Ala peptidase transferred to EC 3.5.1.28 3.4.19.11 gamma-D-glutamyl-meso-diaminopimelate peptidase - 3.4.19.12 ubiquitinyl hydrolase 1 - 3.4.19.13 glutathione gamma-glutamate hydrolase - 3.4.19.14 leukotriene-C4 hydrolase - 3.4.19.15 desampylase - 3.4.19.16 glucosinolate gamma-glutamyl hydrolase - 3.4.19.2 peptidyl-glycinamidase - 3.4.19.3 pyroglutamyl-peptidase I - 3.4.19.4 N-acetylmethionylpeptide peptidase deleted 3.4.19.5 beta-aspartyl-peptidase - 3.4.19.6 pyroglutamyl-peptidase II - 3.4.19.7 N-Formylmethionyl-peptidase - 3.4.19.8 recommended Name never specified transferred to EC 3.4.17.21 3.4.19.9 folate gamma-glutamyl hydrolase - 3.4.2.1 carboxypeptidase A transferred to EC 3.4.17.1 3.4.2.2 carboxypeptidase B transferred to EC 3.4.17.2 3.4.2.3 yeast carboxypeptidase transferred to EC 3.4.17.4 3.4.21.1 chymotrypsin - 3.4.21.10 acrosin - 3.4.21.100 sedolisin - 3.4.21.101 xanthomonalisin - 3.4.21.102 C-terminal processing peptidase - 3.4.21.103 physarolisin - 3.4.21.104 mannan-binding lectin-associated serine protease-2 - 3.4.21.105 rhomboid protease - 3.4.21.106 hepsin - 3.4.21.107 peptidase Do - 3.4.21.108 HtrA2 peptidase - 3.4.21.109 matriptase - 3.4.21.11 elastase transferred to EC 3.4.21.36, EC 3.4.21.37 3.4.21.110 C5a peptidase - 3.4.21.111 aqualysin 1 - 3.4.21.112 site-1 protease - 3.4.21.113 pestivirus NS3 polyprotein peptidase - 3.4.21.114 equine arterivirus serine peptidase - 3.4.21.115 infectious pancreatic necrosis birnavirus Vp4 peptidase - 3.4.21.116 SpoIVB peptidase - 3.4.21.117 stratum corneum chymotryptic enzyme - 3.4.21.118 kallikrein 8 - 3.4.21.119 kallikrein 13 - 3.4.21.12 alpha-lytic endopeptidase - 3.4.21.120 oviductin - 3.4.21.121 Lys-Lys/Arg-Xaa endopeptidase - 3.4.21.122 transmembrane protease serine 2 - 3.4.21.13 phaseolus proteinase transferred to EC 3.4.16.1 3.4.21.14 microbial serine proteases transferred to EC 3.4.21.62, EC 3.4.21.63, EC 3.4.21.64, EC 3.4.21.65, EC 3.4.21.66, EC 3.4.21.67 3.4.21.15 Aspergillus alkaline proteinase transferred to EC 3.4.21.63 3.4.21.16 Alternaria serine proteinase deleted 3.4.21.17 Arthrobacter serine proteinase deleted 3.4.21.18 Tenebrio alpha-proteinase deleted 3.4.21.19 glutamyl endopeptidase - 3.4.21.2 chymotrypsin C - 3.4.21.20 cathepsin G - 3.4.21.21 coagulation factor VIIa - 3.4.21.22 coagulation factor IXa - 3.4.21.23 Vipera russelli proteinase deleted 3.4.21.24 red cell neutral endopeptidase deleted 3.4.21.25 cucumisin - 3.4.21.26 prolyl oligopeptidase - 3.4.21.27 coagulation factor XIa - 3.4.21.28 Agkistrodon serine proteinase transferred to EC 3.4.21.74 3.4.21.29 Bothrops atrox serine proteinase transferred to EC 3.4.21.74 3.4.21.3 metridin - 3.4.21.30 Crotalus adamanteus serine proteinase transferred to EC 3.4.21.74 3.4.21.31 urokinase transferred to EC 3.4.21.68, EC 3.4.21.73 3.4.21.32 brachyurin - 3.4.21.33 Entomophthora collagenolytic proteinase deleted 3.4.21.34 plasma kallikrein - 3.4.21.35 tissue kallikrein - 3.4.21.36 pancreatic elastase - 3.4.21.37 leukocyte elastase - 3.4.21.38 coagulation factor XIIa - 3.4.21.39 chymase - 3.4.21.4 trypsin - 3.4.21.40 submandibular proteinase A deleted 3.4.21.41 complement subcomponent C1r - 3.4.21.42 complement subcomponent C1s - 3.4.21.43 classical-complement-pathway C3/C5 convertase - 3.4.21.44 complement component C5 convertase transferred to EC 3.4.21.43 3.4.21.45 complement factor I - 3.4.21.46 complement factor D - 3.4.21.47 alternative-complement-pathway C3/C5 convertase - 3.4.21.48 cerevisin - 3.4.21.49 hypodermin C - 3.4.21.5 thrombin - 3.4.21.50 lysyl endopeptidase - 3.4.21.51 leukocyte-membrane neutral endopeptidase deleted 3.4.21.52 cathepsin R deleted 3.4.21.53 Endopeptidase La - 3.4.21.54 gamma-Renin - 3.4.21.55 Venombin AB - 3.4.21.56 euphorbain deleted 3.4.21.57 Leucyl endopeptidase - 3.4.21.58 prohormone serine proteinase deleted 3.4.21.59 Tryptase - 3.4.21.6 coagulation factor Xa - 3.4.21.60 Scutelarin - 3.4.21.61 Kexin - 3.4.21.62 Subtilisin - 3.4.21.63 Oryzin - 3.4.21.64 peptidase K - 3.4.21.65 Thermomycolin - 3.4.21.66 Thermitase - 3.4.21.67 Endopeptidase So - 3.4.21.68 t-Plasminogen activator - 3.4.21.69 Protein C (activated) - 3.4.21.7 plasmin - 3.4.21.70 Pancreatic endopeptidase E - 3.4.21.71 Pancreatic elastase II - 3.4.21.72 IgA-specific serine endopeptidase - 3.4.21.73 u-Plasminogen activator - 3.4.21.74 venombin A - 3.4.21.75 Furin - 3.4.21.76 Myeloblastin - 3.4.21.77 semenogelase - 3.4.21.78 granzyme A - 3.4.21.79 granzyme B - 3.4.21.8 kallikrein transferred to EC 3.4.21.34, EC 3.4.21.35 3.4.21.80 Streptogrisin A - 3.4.21.81 Streptogrisin B - 3.4.21.82 Glutamyl endopeptidase II - 3.4.21.83 Oligopeptidase B - 3.4.21.84 limulus clotting factor C - 3.4.21.85 limulus clotting factor B - 3.4.21.86 Limulus clotting enzyme - 3.4.21.87 omptin transferred to EC 3.4.23.49 3.4.21.88 Repressor LexA - 3.4.21.89 Signal peptidase I - 3.4.21.9 enteropeptidase - 3.4.21.90 Togavirin - 3.4.21.91 Flavivirin - 3.4.21.92 Endopeptidase Clp - 3.4.21.93 Proprotein convertase 1 - 3.4.21.94 proprotein convertase 2 - 3.4.21.95 Snake venom factor V activator - 3.4.21.96 Lactocepin - 3.4.21.97 assemblin - 3.4.21.98 hepacivirin - 3.4.21.99 spermosin - 3.4.21.B1 hyaluronan-binding serine protease preliminary BRENDA-supplied EC number 3.4.21.B10 neurosin preliminary BRENDA-supplied EC number 3.4.21.B12 prostase preliminary BRENDA-supplied EC number 3.4.21.B2 granzyme M preliminary BRENDA-supplied EC number 3.4.21.B21 trepolisin preliminary BRENDA-supplied EC number 3.4.21.B24 proprotein convertase 4 preliminary BRENDA-supplied EC number 3.4.21.B25 PACE4 proprotein convertase preliminary BRENDA-supplied EC number 3.4.21.B26 proprotein convertase 5 preliminary BRENDA-supplied EC number 3.4.21.B27 proprotein convertase 7 preliminary BRENDA-supplied EC number 3.4.21.B28 fibroblast activation protein alpha subunit preliminary BRENDA-supplied EC number 3.4.21.B3 duodenase preliminary BRENDA-supplied EC number 3.4.21.B30 UmuD protein preliminary BRENDA-supplied EC number 3.4.21.B34 tricorn core protease (archaea) preliminary BRENDA-supplied EC number 3.4.21.B39 stratum corneum tryptic enzyme preliminary BRENDA-supplied EC number 3.4.21.B4 granzyme K preliminary BRENDA-supplied EC number 3.4.21.B40 kallikrein 9 preliminary BRENDA-supplied EC number 3.4.21.B41 kallikrein 10 preliminary BRENDA-supplied EC number 3.4.21.B42 hippostasin preliminary BRENDA-supplied EC number 3.4.21.B43 kallikrein 12 preliminary BRENDA-supplied EC number 3.4.21.B45 kallikrein 14 preliminary BRENDA-supplied EC number 3.4.21.B48 kumamolysin preliminary BRENDA-supplied EC number 3.4.21.B49 ctpB peptidase preliminary BRENDA-supplied EC number 3.4.21.B5 mast cell protease 5 preliminary BRENDA-supplied EC number 3.4.21.B50 DegQ peptidase preliminary BRENDA-supplied EC number 3.4.21.B52 thermostable serine endopeptidase (Sulfolobus) preliminary BRENDA-supplied EC number 3.4.21.B54 Pyrococcus abyssi serine endopeptidase preliminary BRENDA-supplied EC number 3.4.21.B55 pyrolysin preliminary BRENDA-supplied EC number 3.4.21.B56 Pyrococcus horikoshii membrane protease PH1510 preliminary BRENDA-supplied EC number 3.4.21.B57 pernisine preliminary BRENDA-supplied EC number 3.4.21.B58 pernilase preliminary BRENDA-supplied EC number 3.4.21.B59 granzyme H preliminary BRENDA-supplied EC number 3.4.21.B6 prostasin preliminary BRENDA-supplied EC number 3.4.21.B60 transmembrane protease serine 2 deleted, replaced by EC 3.4.21.122 3.4.21.B61 transmembrane protease serine 11D preliminary BRENDA-supplied EC number 3.4.21.B7 mannan-binding lectin-associated serine protease 1 preliminary BRENDA-supplied EC number 3.4.22.1 cathepsin B - 3.4.22.10 streptopain - 3.4.22.11 insulinase transferred to EC 3.4.99.45 3.4.22.12 gamma-glutamyl hydrolase transferred to EC 3.4.19.9 3.4.22.13 staphylococcal cysteine proteinase deleted 3.4.22.14 actinidain - 3.4.22.15 cathepsin L - 3.4.22.16 cathepsin H - 3.4.22.17 calpain transferred to EC 3.4.22.52 and EC 3.4.22.53 3.4.22.18 prolyl endopeptidase (thiol-dependent) transferred to EC 3.4.21.26 3.4.22.19 endo-oligopeptidase transferred to EC 3.4.24.15 3.4.22.2 papain - 3.4.22.20 dinorphin-converting enzyme deleted 3.4.22.21 yeast cysteine proteinase E transferred to EC 3.4.99.46 3.4.22.22 yeast cysteine proteinase D transferred to EC 3.4.24.37 3.4.22.23 yeast cysteine proteinase F transferred to EC 3.4.21.61 3.4.22.24 cathepsin T - 3.4.22.25 glycyl endopeptidase - 3.4.22.26 cancer procoagulant - 3.4.22.27 cathepsin S - 3.4.22.28 picornain 3C - 3.4.22.29 picornain 2A - 3.4.22.3 ficain - 3.4.22.30 Caricain - 3.4.22.31 Ananain - 3.4.22.32 Stem bromelain - 3.4.22.33 Fruit bromelain - 3.4.22.34 Legumain - 3.4.22.35 Histolysain - 3.4.22.36 caspase-1 - 3.4.22.37 gingipain R - 3.4.22.38 cathepsin K - 3.4.22.39 adenain - 3.4.22.4 bromelain (stem) transferred to EC 3.4.22.32, EC 3.4.22.33 3.4.22.40 bleomycin hydrolase - 3.4.22.41 cathepsin F - 3.4.22.42 cathepsin O - 3.4.22.43 cathepsin V - 3.4.22.44 nuclear-inclusion-a endopeptidase - 3.4.22.45 helper-component proteinase - 3.4.22.46 L-peptidase - 3.4.22.47 gingipain K - 3.4.22.48 staphopain - 3.4.22.49 separase - 3.4.22.5 bromelain (juice) transferred to EC 3.4.22.33 3.4.22.50 V-cath endopeptidase - 3.4.22.51 cruzipain - 3.4.22.52 calpain-1 - 3.4.22.53 calpain-2 - 3.4.22.54 calpain-3 - 3.4.22.55 caspase-2 - 3.4.22.56 caspase-3 - 3.4.22.57 caspase-4 - 3.4.22.58 caspase-5 - 3.4.22.59 caspase-6 - 3.4.22.6 chymopapain - 3.4.22.60 caspase-7 - 3.4.22.61 caspase-8 - 3.4.22.62 caspase-9 - 3.4.22.63 caspase-10 - 3.4.22.64 caspase-11 - 3.4.22.65 peptidase 1 (mite) - 3.4.22.66 calicivirin - 3.4.22.67 zingipain - 3.4.22.68 Ulp1 peptidase - 3.4.22.69 SARS coronavirus main proteinase - 3.4.22.7 asclepain - 3.4.22.70 sortase A - 3.4.22.71 sortase B - 3.4.22.8 clostripain - 3.4.22.9 yeast proteinase B transferred to EC 3.4.21.48 3.4.22.B1 vignain preliminary BRENDA-supplied EC number 3.4.22.B14 papain-like proteinase 1 preliminary BRENDA-supplied EC number 3.4.22.B15 rabbit hemorrhagic disease virus 3C-like protease preliminary BRENDA-supplied EC number 3.4.22.B19 YopJ protease preliminary BRENDA-supplied EC number 3.4.22.B20 PfpI endopeptidase preliminary BRENDA-supplied EC number 3.4.22.B24 calpain 4 preliminary BRENDA-supplied EC number 3.4.22.B25 calpain 5 preliminary BRENDA-supplied EC number 3.4.22.B26 calpain 6 preliminary BRENDA-supplied EC number 3.4.22.B27 calpain 7 preliminary BRENDA-supplied EC number 3.4.22.B28 calpain 8 preliminary BRENDA-supplied EC number 3.4.22.B29 calpain 9 preliminary BRENDA-supplied EC number 3.4.22.B30 calpain 10 preliminary BRENDA-supplied EC number 3.4.22.B31 calpain 11 preliminary BRENDA-supplied EC number 3.4.22.B32 calpain 12 preliminary BRENDA-supplied EC number 3.4.22.B35 calpain 15 preliminary BRENDA-supplied EC number 3.4.22.B36 calpain A preliminary BRENDA-supplied EC number 3.4.22.B37 calpain B preliminary BRENDA-supplied EC number 3.4.22.B38 calpain C preliminary BRENDA-supplied EC number 3.4.22.B47 legume cysteine endopeptidase preliminary BRENDA-supplied EC number 3.4.22.B49 cathepsin L1 preliminary BRENDA-supplied EC number 3.4.22.B5 CPB protease preliminary BRENDA-supplied EC number 3.4.22.B50 papain-like proteinase 2 preliminary BRENDA-supplied EC number 3.4.22.B6 cathepsin B-like protease preliminary BRENDA-supplied EC number 3.4.22.B60 cathepsin L2 preliminary BRENDA-supplied EC number 3.4.22.B61 cathepsin L5 preliminary BRENDA-supplied EC number 3.4.22.B62 cathepsin L3 preliminary BRENDA-supplied EC number 3.4.22.B63 sortase C preliminary BRENDA-supplied EC number 3.4.22.B64 sortase D preliminary BRENDA-supplied EC number 3.4.22.B65 cathepsin P preliminary BRENDA-supplied EC number 3.4.22.B66 caspase-12 preliminary BRENDA-supplied EC number 3.4.22.B67 Ulp2 peptidase preliminary BRENDA-supplied EC number 3.4.22.B68 EhCP4 proteinase preliminary BRENDA-supplied EC number 3.4.22.B69 falcipain-2 preliminary BRENDA-supplied EC number 3.4.22.B70 SENP1 peptidase preliminary BRENDA-supplied EC number 3.4.22.B71 SENP2 peptidase preliminary BRENDA-supplied EC number 3.4.22.B72 SENP3 peptidase preliminary BRENDA-supplied EC number 3.4.22.B73 SENP5 peptidase preliminary BRENDA-supplied EC number 3.4.22.B74 SENP6 peptidase preliminary BRENDA-supplied EC number 3.4.22.B75 SENP7 peptidase preliminary BRENDA-supplied EC number 3.4.22.B76 Allium alpha-fibrinogenase AFTEII preliminary BRENDA-supplied EC number 3.4.22.B77 Sulfolobus solfataricus peptidase preliminary BRENDA-supplied EC number 3.4.22.B78 endopepidase PH1704 preliminary BRENDA-supplied EC number 3.4.22.B79 nsP2 protease preliminary BRENDA-supplied EC number 3.4.22.B8 Tpr proteinase (Porphyromonas gingivalis) preliminary BRENDA-supplied EC number 3.4.22.B80 SARS-CoV papain-like protease preliminary BRENDA-supplied EC number 3.4.23.1 pepsin A - 3.4.23.10 endothia acid proteinase transferred to EC 3.4.23.22 3.4.23.11 thyroid aspartic proteinase deleted 3.4.23.12 nepenthesin - 3.4.23.13 Lotus aspartic proteinase deleted 3.4.23.14 sorghum aspartic proteinase deleted 3.4.23.15 renin - 3.4.23.16 HIV-1 retropepsin - 3.4.23.17 Pro-opiomelanocortin converting enzyme - 3.4.23.18 Aspergillopepsin I - 3.4.23.19 Aspergillopepsin II - 3.4.23.2 pepsin B - 3.4.23.20 Penicillopepsin - 3.4.23.21 Rhizopuspepsin - 3.4.23.22 Endothiapepsin - 3.4.23.23 Mucorpepsin - 3.4.23.24 Candidapepsin - 3.4.23.25 saccharopepsin - 3.4.23.26 Rhodotorulapepsin - 3.4.23.27 physaropepsin transferred to EC 3.4.21.103 3.4.23.28 Acrocylindropepsin - 3.4.23.29 Polyporopepsin - 3.4.23.3 gastricsin - 3.4.23.30 Pycnoporopepsin - 3.4.23.31 Scytalidopepsin A - 3.4.23.32 Scytalidopepsin B - 3.4.23.33 xanthomonapepsin transferred to EC 3.4.21.101 3.4.23.34 cathepsin E - 3.4.23.35 Barrierpepsin - 3.4.23.36 Signal peptidase II - 3.4.23.37 pseudomonapepsin transferred to EC 3.4.21.100 3.4.23.38 plasmepsin I - 3.4.23.39 plasmepsin II - 3.4.23.4 chymosin - 3.4.23.40 Phytepsin - 3.4.23.41 yapsin 1 - 3.4.23.42 thermopsin - 3.4.23.43 prepilin peptidase - 3.4.23.44 nodavirus endopeptidase - 3.4.23.45 memapsin 1 - 3.4.23.46 memapsin 2 - 3.4.23.47 HIV-2 retropepsin - 3.4.23.48 plasminogen activator Pla - 3.4.23.49 omptin - 3.4.23.5 cathepsin D - 3.4.23.50 human endogenous retrovirus K endopeptidase - 3.4.23.51 HycI peptidase - 3.4.23.52 preflagellin peptidase - 3.4.23.6 microbial carboxyl proteinases deleted, included in EC 3.4.23.18-28, EC 3.4.23.30 3.4.23.7 Penicillium janthinellum acid proteinase transferred to EC 3.4.23.20 3.4.23.8 yeast proteinase A transferred to EC 3.4.23.25 3.4.23.9 rhizopus acid proteinase transferred to EC 3.4.23.21 3.4.23.B1 napsin preliminary BRENDA-supplied EC number 3.4.23.B10 Rous sarcoma virus retropepsin preliminary BRENDA-supplied EC number 3.4.23.B11 spumapepsin preliminary BRENDA-supplied EC number 3.4.23.B13 proteinase P15 preliminary BRENDA-supplied EC number 3.4.23.B14 plasmepsin IV preliminary BRENDA-supplied EC number 3.4.23.B17 walleye dermal sarcoma virus proteinase preliminary BRENDA-supplied EC number 3.4.23.B18 mouse mammary tumor virus retropepsin preliminary BRENDA-supplied EC number 3.4.23.B19 plasmepsin V preliminary BRENDA-supplied EC number 3.4.23.B2 Simian immunodeficiency virus proteinase preliminary BRENDA-supplied EC number 3.4.23.B20 HycD peptidase preliminary BRENDA-supplied EC number 3.4.23.B24 signal peptide peptidase preliminary BRENDA-supplied EC number 3.4.23.B25 thermopsin-like protease SSO1175 preliminary BRENDA-supplied EC number 3.4.23.B3 equine infectious anemia virus proteinase preliminary BRENDA-supplied EC number 3.4.23.B4 Feline immunodeficiency virus protease preliminary BRENDA-supplied EC number 3.4.23.B5 murine leukemia virus protease preliminary BRENDA-supplied EC number 3.4.23.B6 Mason-Pfizer monkey virus proteinase preliminary BRENDA-supplied EC number 3.4.23.B8 human T-cell leukemia virus type 1 protease preliminary BRENDA-supplied EC number 3.4.23.B9 bovine leukemia virus protease preliminary BRENDA-supplied EC number 3.4.24.1 atrolysin A - 3.4.24.10 Trichophyton mentagrophytes keratinase deleted 3.4.24.11 neprilysin - 3.4.24.12 envelysin - 3.4.24.13 IgA-specific metalloendopeptidase - 3.4.24.14 procollagen N-endopeptidase - 3.4.24.15 thimet oligopeptidase - 3.4.24.16 neurolysin - 3.4.24.17 stromelysin 1 - 3.4.24.18 meprin A - 3.4.24.19 procollagen C-endopeptidase - 3.4.24.2 Sepia proteinase deleted 3.4.24.20 peptidyl-Lys metalloendopeptidase - 3.4.24.21 astacin - 3.4.24.22 stromelysin 2 - 3.4.24.23 matrilysin - 3.4.24.24 gelatinase A - 3.4.24.25 vibriolysin - 3.4.24.26 pseudolysin - 3.4.24.27 thermolysin - 3.4.24.28 bacillolysin - 3.4.24.29 aureolysin - 3.4.24.3 microbial collagenase - 3.4.24.30 coccolysin - 3.4.24.31 mycolysin - 3.4.24.32 beta-Lytic metalloendopeptidase - 3.4.24.33 peptidyl-Asp metalloendopeptidase - 3.4.24.34 neutrophil collagenase - 3.4.24.35 gelatinase B - 3.4.24.36 leishmanolysin - 3.4.24.37 saccharolysin - 3.4.24.38 gametolysin - 3.4.24.39 deuterolysin - 3.4.24.4 microbial metalloproteinases transferred to EC 3.4.24.25-32, EC 3.4.24.39, EC 3.4.24.40 3.4.24.40 serralysin - 3.4.24.41 atrolysin B - 3.4.24.42 atrolysin C - 3.4.24.43 atroxase - 3.4.24.44 atrolysin E - 3.4.24.45 atrolysin F - 3.4.24.46 adamalysin - 3.4.24.47 horrilysin - 3.4.24.48 ruberlysin - 3.4.24.49 bothropasin - 3.4.24.5 lens neutral proteinase deleted, included in EC 3.4.22.17, EC 3.4.25.1 3.4.24.50 bothrolysin - 3.4.24.51 ophiolysin - 3.4.24.52 trimerelysin I - 3.4.24.53 trimerelysin II - 3.4.24.54 mucrolysin - 3.4.24.55 pitrilysin - 3.4.24.56 insulysin - 3.4.24.57 O-sialoglycoprotein endopeptidase - 3.4.24.58 russellysin - 3.4.24.59 mitochondrial intermediate peptidase - 3.4.24.6 leucolysin - 3.4.24.60 dactylysin - 3.4.24.61 nardilysin - 3.4.24.62 magnolysin - 3.4.24.63 meprin B - 3.4.24.64 mitochondrial processing peptidase - 3.4.24.65 macrophage elastase - 3.4.24.66 choriolysin L - 3.4.24.67 choriolysin H - 3.4.24.68 tentoxilysin - 3.4.24.69 bontoxilysin - 3.4.24.7 interstitial collagenase - 3.4.24.70 oligopeptidase A - 3.4.24.71 endothelin-converting enzyme 1 - 3.4.24.72 fibrolase - 3.4.24.73 jararhagin - 3.4.24.74 fragilysin - 3.4.24.75 lysostaphin - 3.4.24.76 flavastacin - 3.4.24.77 snapalysin - 3.4.24.78 gpr endopeptidase - 3.4.24.79 pappalysin-1 - 3.4.24.8 Achromobacter iophagus collagenase transferred to EC 3.4.24.3 3.4.24.80 membrane-type matrix metalloproteinase-1 - 3.4.24.81 ADAM10 endopeptidase - 3.4.24.82 ADAMTS-4 endopeptidase - 3.4.24.83 anthrax lethal factor endopeptidase - 3.4.24.84 Ste24 endopeptidase - 3.4.24.85 S2P endopeptidase - 3.4.24.86 ADAM 17 endopeptidase - 3.4.24.87 ADAMTS13 endopeptidase - 3.4.24.88 desampylase transferred to EC 3.4.19.15 3.4.24.89 Pro-Pro endopeptidase - 3.4.24.9 Trichophyton schoenleinii collagenase deleted 3.4.24.B10 ADAM12 endopeptidase preliminary BRENDA-supplied EC number 3.4.24.B11 ADAMTS1 endopeptidase preliminary BRENDA-supplied EC number 3.4.24.B12 ADAMTS5 endopeptidase preliminary BRENDA-supplied EC number 3.4.24.B14 neprilysin-2 preliminary BRENDA-supplied EC number 3.4.24.B15 PHEX peptidase preliminary BRENDA-supplied EC number 3.4.24.B16 protease lasA preliminary BRENDA-supplied EC number 3.4.24.B17 FtsH endopeptidase preliminary BRENDA-supplied EC number 3.4.24.B18 m-AAA protease preliminary BRENDA-supplied EC number 3.4.24.B19 i-AAA protease preliminary BRENDA-supplied EC number 3.4.24.B2 oligoendopeptidase F preliminary BRENDA-supplied EC number 3.4.24.B20 FtsH protease preliminary BRENDA-supplied EC number 3.4.24.B23 stage IV sporulation protein FB preliminary BRENDA-supplied EC number 3.4.24.B24 L-alanine-D-glutamate endopeptidase preliminary BRENDA-supplied EC number 3.4.24.B25 MAHCE preliminary BRENDA-supplied EC number 3.4.24.B26 myroilysin preliminary BRENDA-supplied EC number 3.4.24.B27 ADAM19 preliminary BRENDA-supplied EC number 3.4.24.B28 ADAM15 preliminary BRENDA-supplied EC number 3.4.24.B29 Sulfolobus solfataricus metalloendopeptidase preliminary BRENDA-supplied EC number 3.4.24.B3 matrix metalloproteinase-11 preliminary BRENDA-supplied EC number 3.4.24.B30 aeropyrolysin preliminary BRENDA-supplied EC number 3.4.24.B33 Vipera ammodytes ammodytes metalloproteinase VaH3 preliminary BRENDA-supplied EC number 3.4.24.B34 Vipera ammodytes ammodytes metalloproteinase VaF1 preliminary BRENDA-supplied EC number 3.4.24.B35 Vipera ammodytes ammodytes metalloproteinase VaH4 preliminary BRENDA-supplied EC number 3.4.24.B36 Vipera ammodytes ammodytes metalloproteinase VaH1 preliminary BRENDA-supplied EC number 3.4.24.B37 mutalysin II preliminary BRENDA-supplied EC number 3.4.24.B38 ammodytagin preliminary BRENDA-supplied EC number 3.4.24.B39 metallo-alpha-fibrinogenase preliminary BRENDA-supplied EC number 3.4.24.B4 matrix metalloproteinase-13 preliminary BRENDA-supplied EC number 3.4.24.B40 ADAM 13 enpopeptidase preliminary BRENDA-supplied EC number 3.4.24.B5 matrix metalloproteinase-15 preliminary BRENDA-supplied EC number 3.4.24.B6 matrix metalloproteinase-20 preliminary BRENDA-supplied EC number 3.4.24.B7 matrix metalloproteinase-26 preliminary BRENDA-supplied EC number 3.4.24.B8 ADAM1 endopeptidase preliminary BRENDA-supplied EC number 3.4.24.B9 ADAM9 endopeptidase preliminary BRENDA-supplied EC number 3.4.25.1 proteasome endopeptidase complex - 3.4.25.2 HslU-HslV peptidase - 3.4.3.1 glycyl-glycine dipeptidase transferred to EC 3.4.13.18 3.4.3.2 glycyl-leucine dipeptidase transferred to EC 3.4.13.18 3.4.3.3 aminoacyl-histidine dipeptidase, carnosinase transferred to EC 3.4.13.3 3.4.3.4 aminoacyl-methylhistidine dipeptidase, anserinase transferred to EC 3.4.13.5 3.4.3.5 cysteinyl-glycine dipeptidase transferred to EC 3.4.11.2 3.4.3.6 iminodipeptidase transferred to EC 3.4.13.18 3.4.3.7 imidodipeptidase, prolidase transferred to EC 3.4.13.9 3.4.4.1 pepsin transferred to EC 3.4.23.1 3.4.4.10 papain transferred to EC 3.4.22.2 3.4.4.11 chymopapain transferred to EC 3.4.22.6 3.4.4.12 ficin transferred to EC 3.4.22.3 3.4.4.13 thrombin transferred to EC 3.4.21.5 3.4.4.14 plasmin transferred to EC 3.4.21.7 3.4.4.15 renin transferred to EC 3.4.23.15 3.4.4.16 subtilopeptidase A transferred to EC 3.4.21.62, EC 3.4.21.63, EC 3.4.21.64, EC 3.4.21.65, EC 3.4.21.66, EC 3.4.21.67 3.4.4.17 aspergillopeptidase A transferred to EC 3.4.23.20, EC 3.4.23.21, EC 3.4.23.22, EC 3.4.23.23, EC 3.4.23.24, EC 3.4.23.25, EC 3.4.23.26, EC 3.4.21.103, EC 3.4.23.28, EC 3.4.23.29, and EC 3.4.23.30 -30 3.4.4.18 streptococcus peptidase A transferred to EC 3.4.22.10 3.4.4.19 clostridiopeptidase A transferred to EC 3.4.24.3 3.4.4.2 pepsin B transferred to EC 3.4.23.2 3.4.4.20 clostridiopeptidase B transferred to EC 3.4.22.8 3.4.4.21 kallikrein transferred to EC 3.4.21.34 and EC 3.4.21.35 3.4.4.22 recommended Name never specified transferred to EC 3.4.23.3 3.4.4.23 recommended Name never specified transferred to EC 3.4.23.5 3.4.4.24 recommended Name never specified transferred to EC 3.4.22.32, EC 3.4.22.33 3.4.4.25 keratinase deleted 3.4.4.3 rennin transferred to EC 3.4.23.4 3.4.4.4 trypsin transferred to EC 3.4.21.4 3.4.4.5 chymotrypsin transferred to EC 3.4.21.1 3.4.4.6 chymotrypsin B transferred to EC 3.4.21.1 3.4.4.7 pancreatopeptidase E transferred to EC 3.4.21.36, EC 3.4.21.37 3.4.4.8 enteropeptidase transferred to EC 3.4.21.9 3.4.4.9 cathepsin C transferred to EC 3.4.14.1 3.4.99.1 acrocylindricum proteinase transferred to EC 3.4.23.28 3.4.99.10 insulinase transferred to EC 3.4.24.56 3.4.99.11 Streptomyces alkalophilic keratinase deleted 3.4.99.12 Trichophyton mentagrophytes keratinase deleted 3.4.99.13 beta-lytic proteinase (Mycobacterium sorangium) transferred to EC 3.4.24.32 3.4.99.14 mexicanain deleted 3.4.99.15 Paecilomyces proteinase deleted 3.4.99.16 Penicillium notatum extracellular proteinase deleted 3.4.99.17 peptidoglycan endopeptidase deleted 3.4.99.18 pinguinain deleted 3.4.99.19 renin transferred to EC 3.4.23.15 3.4.99.2 agavain deleted 3.4.99.20 scopulariopsis proteinase deleted 3.4.99.21 solanain deleted 3.4.99.22 staphylokinase transferred to EC 3.4.24.29 3.4.99.23 tabernamontanain deleted 3.4.99.24 Tenebrio alpha-proteinase deleted 3.4.99.25 trametes acid proteinase transferred to EC 3.4.23.21 3.4.99.26 urokinase transferred to EC 3.4.21.7, EC 3.4.21.68 3.4.99.27 Echis carinatus prothrombin-activating proteinase deleted 3.4.99.28 Oxyuranus scutellatus prothrombin-activating proteinase transferred to EC 3.4.21.60 3.4.99.29 Myxobacter AL-1 proteinase I deleted 3.4.99.3 angiotensinase deleted 3.4.99.30 Myxobacter AL-1 proteinase II transferred to EC 3.4.24.20 3.4.99.31 Tissue endopeptidase degrading collagenase synthetic substrate transferred to EC 3.4.24.15 3.4.99.32 Armillaria mellea neutral proteinase transferred to EC 3.4.24.20 3.4.99.33 cathepsin R deleted 3.4.99.34 mytilidase deleted 3.4.99.35 premurein-leader peptidase transferred to EC 3.4.23.36 3.4.99.36 leader peptidase transferred to EC 3.4.21.89 3.4.99.37 RecA peptidase deleted 3.4.99.38 pro-opiomelanotropin-converting proteinase transferred to EC 3.4.23.17 3.4.99.39 pseudomurein endopeptidase deleted 3.4.99.4 aspartylendopeptidase transferred to EC 3.4.23.12 3.4.99.40 pro-gonadoliberin proteinase deleted 3.4.99.41 mitochondrial processing peptidase transferred to EC 3.4.24.64 3.4.99.42 leucyllysine endopeptidase deleted 3.4.99.43 thermopsin transferred to EC 3.4.23.42 3.4.99.44 pitrilysin transferred to EC 3.4.24.55 3.4.99.45 insulinase transferred to EC 3.4.24.56 3.4.99.46 multicatalytic endopeptidase complex transferred to EC 3.4.25.1 3.4.99.5 Clostridium histolyticum collagenase 2 transferred to EC 3.4.24.3 3.4.99.6 crayfish low-molecular-weight proteinase transferred to EC 3.4.24.21 3.4.99.7 euphorbain deleted 3.4.99.8 Gliocladium proteinase deleted 3.4.99.9 hurain deleted 3.4.99.B1 RCE1 preliminary BRENDA-supplied EC number 3.4.99.B2 D-aspartyl endopeptidase preliminary BRENDA-supplied EC number