3.4.22.52	Retinitis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34078571&form=6&db=m	Evidence for the involvement of interleukin-1? during development of experimental cytomegalovirus retinitis in immunosuppressed mice.	causal interaction,unassigned	1,0	
3.4.22.52	Colitis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34162146&form=6&db=m	Melatonin-mediated MT2 attenuates colitis induced by dextran sodium sulfate via PI3K/AKT/Nrf2/SIRT1/ROR?/NF-?B signaling pathways.	causal interaction,therapeutic application,unassigned	1,1,0	
3.4.22.52	Muscular Atrophy	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34319828&form=6&db=m	A semiautomated measurement of muscle fiber size using the Imaris software.	causal interaction,unassigned	2,0	
3.4.22.52	Breast Neoplasms	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34381117&form=6&db=m	Cleavage and activation of LIM kinase 1 as a novel mechanism for calpain 2-mediated regulation of nuclear dynamics.	ongoing research,unassigned	4,0	
3.4.22.52	Neurodegenerative Diseases	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34430716&form=6&db=m	Calpain-1 C2L domain peptide protects mouse hippocampus-derived neuronal HT22 cells against glutamate-induced oxytosis.	unassigned	-	
3.4.22.52	Heart Failure	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34524407&form=6&db=m	Calpain-2 Specifically Cleaves Junctophilin-2 at the Same Site as Calpain-1 but with Less Efficacy.	causal interaction,therapeutic application,unassigned	3,3,0