3.4.22.52	casein + H2O	-	Bos taurus	?	-	?	15445	
3.4.22.52	Frizzled-7 + H2O	-	Bos taurus	?	-	?	390216	
3.4.22.52	Frizzled-7 + H2O	calpain-1 is a regulator of Frizzled-7 turnover at the plasma membrane	Bos taurus	?	-	?	390216	
3.4.22.52	additional information	primary role of calpain 1 and calpain 3 in meat tenderization	Bos taurus	?	-	?	89	
3.4.22.52	additional information	because the calcium concentration in postmortem muscle is high enough to activate mu-calpain, but not m-calpain, it seems reasonable to conclude that mu-calpain is responsible for postmortem degradation of calpastatin. Degradation of calpastatin by mu-calpain reduces calpain-inhibitory activity and is probably an important event in regulation of postmortem proteolysis, and, thus, meat tenderness	Bos taurus	?	-	?	89	
3.4.22.52	additional information	calpastatin could play an important role in preventing uncontrolled activity of l-calpain which otherwise may facilitate pulmonary hypertension, smooth muscle proliferation and apoptosis	Bos taurus	?	-	?	89	
3.4.22.52	myofibril + H2O	-	Bos taurus	?	-	?	432158	
3.4.22.52	RhoA + H2O	-	Bos taurus	?	-	?	358976	
3.4.22.52	RhoA + H2O	calpain cleaves RhoA and generates a form that inhibits integrin-induced stress fiber assembly and cell spreading	Bos taurus	?	-	?	358976	
3.4.22.52	titin + H2O	pH 7.5, absence or presence of 12 microM calcium	Bos taurus	?	-	?	380771