1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase dermal papilla - 744861 3.4.21.5 thrombin dermal papilla thrombin induces a phosphoinositide 3-kinase-Akt pathway-dependent acquisition of dermal-sheath-like properties by dermal papilla cells in vitro, involving increased proliferation rate, acquisition of myofibroblastic contractile properties and a decreased capacity to sustain growth and survival of keratinocytes. The thrombin inhibitor protease nexin 1 regulates all those effects in vitro. Control of thrombin signaling interferes with hair follicle dermal cells plasticity to regulate their function 699101