1.1.1.205 IMP dehydrogenase CHO cell - 347910 1.1.1.8 glycerol-3-phosphate dehydrogenase (NAD+) CHO cell - 654824 1.14.13.39 nitric-oxide synthase (NADPH) CHO cell - 675520 1.14.13.9 kynurenine 3-monooxygenase CHO cell - 742349 1.14.18.2 CMP-N-acetylneuraminate monooxygenase CHO cell generation of a stable CHO cell line with significantly reduced levels of CMP-Neu5Ac hydroxylase activity and reduced amounts of N-glycolylneuraminic acid, using a rational antisense RNA strategy 658179 1.17.4.1 ribonucleoside-diphosphate reductase CHO cell - 437919 1.3.1.72 DELTA24-sterol reductase CHO cell - 724442 1.3.5.1 succinate dehydrogenase CHO cell - 654199 1.7.3.3 factor-independent urate hydroxylase CHO cell wild-type and PEX5-defective CHO cell lines each stable producing the enzyme 657736 2.3.1.26 sterol O-acyltransferase CHO cell - 486693, 486703, 674216 2.3.1.26 sterol O-acyltransferase CHO cell CHO cells, cultured cells 486677, 486690 2.3.1.50 serine C-palmitoyltransferase CHO cell - 658109, 659868 2.3.1.57 diamine N-acetyltransferase CHO cell - 487265, 662129 2.4.1.101 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase CHO cell wild-type and mutant F6 and F8 488371 2.4.1.101 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase CHO cell wild-type, Lec1 cells are deficient in enzyme activity, mutant Lec1A cells show weak enzyme activity, 2% compared to wild-type, and produce complex N-glycans 488380 2.4.1.102 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase CHO cell - 638279 2.4.1.135 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase CHO cell - 659141, 659435 2.4.1.141 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase CHO cell - 685092 2.4.1.144 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase CHO cell - 638214 2.4.1.144 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase CHO cell LEC10 ovary cell line 488370 2.4.1.144 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase CHO cell ricin resistant mutant 488370 2.4.1.149 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase CHO cell Pro-5 and Lec2 CHO cells 638584 2.4.1.155 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase CHO cell - 736218 2.4.1.198 phosphatidylinositol N-acetylglucosaminyltransferase CHO cell CHO-K1 cell lines G9PLAP and mutant G9PLAP.85 638133 2.4.1.221 peptide-O-fucosyltransferase CHO cell - 441440, 441442, 703986 2.4.1.221 peptide-O-fucosyltransferase CHO cell fucosylation-deficient Lec13 chinese hamster ovary cells have wild-type levels of Pofut1 and cell surface Notch receptors 704420 2.4.1.38 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase CHO cell - 675791 2.4.1.68 glycoprotein 6-alpha-L-fucosyltransferase CHO cell - 441440, 441442, 702784 2.4.1.80 ceramide glucosyltransferase CHO cell strain K1, and GM3-mutant strain Z65 489424 2.4.1.83 dolichyl-phosphate beta-D-mannosyltransferase CHO cell - 658867 2.4.1.83 dolichyl-phosphate beta-D-mannosyltransferase CHO cell CHO 2.38 cel 680743 2.4.1.90 N-acetyllactosamine synthase CHO cell - 675952 2.4.2.31 NAD+-protein-arginine ADP-ribosyltransferase CHO cell - 722180 2.4.2.8 hypoxanthine phosphoribosyltransferase CHO cell - 701888 2.4.3.1 beta-galactoside alpha-(2,6)-sialyltransferase CHO cell - 721384 2.5.1.26 alkylglycerone-phosphate synthase CHO cell - 702411 2.6.1.2 alanine transaminase CHO cell - 737896 2.7.1.138 ceramide kinase CHO cell - 690700 2.7.1.20 adenosine kinase CHO cell - 641111, 660724, 663319 2.7.1.67 1-phosphatidylinositol 4-kinase CHO cell - 723136 2.7.11.11 cAMP-dependent protein kinase CHO cell - 661759 2.7.7.15 choline-phosphate cytidylyltransferase CHO cell - 721712 2.7.7.19 polynucleotide adenylyltransferase CHO cell - 642938 2.7.7.30 fucose-1-phosphate guanylyltransferase CHO cell - 645224 2.7.7.43 N-acylneuraminate cytidylyltransferase CHO cell - 645275 2.7.8.1 ethanolaminephosphotransferase CHO cell - 644415 2.7.8.15 UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase CHO cell - 645359, 645360, 645364, 645366, 645367, 703322 2.7.8.27 sphingomyelin synthase CHO cell - 667767 2.7.8.29 L-serine-phosphatidylethanolamine phosphatidyltransferase CHO cell - 661228, 717758, 717761 2.7.8.5 CDP-diacylglycerol-glycerol-3-phosphate 1-phosphatidyltransferase CHO cell - 644299 2.8.2.8 [heparan sulfate]-glucosamine N-sulfotransferase CHO cell - 645941 3.1.2.2 palmitoyl-CoA hydrolase CHO cell - 646175 3.1.2.20 acyl-CoA hydrolase CHO cell - 646175 3.1.22.1 deoxyribonuclease II CHO cell - 696131 3.1.3.35 thymidylate 5'-phosphatase CHO cell - 81087 3.1.3.36 phosphoinositide 5-phosphatase CHO cell - 677869 3.1.3.4 phosphatidate phosphatase CHO cell - 690815 3.1.4.3 phospholipase C CHO cell stably expressing human imidazoline receptor antisera-selected protein IRAS 681028 3.2.1.106 mannosyl-oligosaccharide glucosidase CHO cell - 694198 3.2.1.166 heparanase CHO cell - 690796, 692520 3.2.1.18 exo-alpha-sialidase CHO cell - 655170, 655171 3.4.11.3 cystinyl aminopeptidase CHO cell - 731661 3.4.16.6 carboxypeptidase D CHO cell - 753046 3.4.17.12 carboxypeptidase M CHO cell - 696532 3.4.17.22 metallocarboxypeptidase D CHO cell - 753046 3.4.21.112 site-1 protease CHO cell - 710345 3.4.21.75 Furin CHO cell - 681690, 700401 3.4.22.15 cathepsin L CHO cell - 753061 3.4.22.56 caspase-3 CHO cell - 696881 3.4.22.60 caspase-7 CHO cell - 696881 3.4.22.61 caspase-8 CHO cell - 666402 3.4.22.61 caspase-8 CHO cell inhibition of caspase-8 enhances the viability of the CHO cells in both batch and fed-batch suspension cultures. Caspase-8 is possible involved in the apoptotic cell death in batch and fed-batch cultures of CHO cells 681759 3.4.22.62 caspase-9 CHO cell inhibition of caspase-9 enhances the viability of the CHO cells in both batch and fed-batch suspension cultures. Caspase-9 is possible involved in the apoptotic cell death in batch and fed-batch cultures of CHO cells 681759 3.4.23.46 memapsin 2 CHO cell - 711091, 711303, 734729 3.4.23.46 memapsin 2 CHO cell inhibitor drugs tested 683381 3.4.23.5 cathepsin D CHO cell - 711533, 753060 3.4.24.85 S2P endopeptidase CHO cell - 735261 3.4.24.86 ADAM 17 endopeptidase CHO cell - 669269 3.4.24.86 ADAM 17 endopeptidase CHO cell mutated sublines M1 and M2. M1 contains only one expressible TACE allele encoding an M435I point mutation in the catalytic center of the protease, and M2 cells produce two TACE variants with distinct point mutations in the catalytic domain (C22Y) and the cysteine-rich/disintegrin domain (C600Y) 669237 3.5.1.23 ceramidase CHO cell - 697229 3.6.5.2 small monomeric GTPase CHO cell - 665471, 719932 3.6.5.5 dynamin GTPase CHO cell - 686581 4.1.1.21 phosphoribosylaminoimidazole carboxylase CHO cell accumulates 5-aminoimidazole ribotide 728311 4.6.1.1 adenylate cyclase CHO cell - 679659, 695074 4.6.1.1 adenylate cyclase CHO cell expresses all nine adenylate cyclase isoforms 678381 5.1.3.7 UDP-N-acetylglucosamine 4-epimerase CHO cell ldlD cells are deficient in UDP-N-acetylglucosamine 4-epimerase 2410 5.6.2.2 DNA topoisomerase (ATP-hydrolysing) CHO cell - 691628 6.1.1.1 tyrosine-tRNA ligase CHO cell - 745300 6.1.1.20 phenylalanine-tRNA ligase CHO cell - 744547 6.1.1.4 leucine-tRNA ligase CHO cell - 693164 6.3.2.17 tetrahydrofolate synthase CHO cell - 744775 6.3.3.2 5-formyltetrahydrofolate cyclo-ligase CHO cell CHO, ovary cell line and its methotrexate resistant subline 1327 7.2.2.9 P-type Cu2+ transporter CHO cell copper-resistant CHO cells which overexpress the enzyme 246912 7.6.2.1 P-type phospholipid transporter CHO cell - 720146 7.6.2.2 ABC-type xenobiotic transporter CHO cell - 733268