1.1.1.102 3-dehydrosphinganine reductase HEK-293 cell - 699413 1.1.1.146 11beta-hydroxysteroid dehydrogenase HEK-293 cell - 691279, 698026, 760685, 761000, 761665, 761758, 762494 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) HEK-293 cell - 728158 1.1.1.188 prostaglandin-F synthase HEK-293 cell embryonic kidney cell, isozyme PGFS-I 654851 1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) HEK-293 cell - 670259 1.1.1.27 L-lactate dehydrogenase HEK-293 cell - 760891 1.1.1.36 acetoacetyl-CoA reductase HEK-293 cell isozymes AKR1B15.1 and AKR1B15.2 740743 1.1.1.41 isocitrate dehydrogenase (NAD+) HEK-293 cell - 741458 1.1.1.42 isocitrate dehydrogenase (NADP+) HEK-293 cell - 698059, 711158 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase HEK-293 cell - 657673, 658489 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase HEK-293 cell low enzyme expression level 669784 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase HEK-293 cell low expression level 669905 1.1.1.62 17beta-estradiol 17-dehydrogenase HEK-293 cell - 657673, 686533 1.1.1.62 17beta-estradiol 17-dehydrogenase HEK-293 cell isozymes AKR1B15.1 and AKR1B15.2 740743 1.1.1.62 17beta-estradiol 17-dehydrogenase HEK-293 cell stable expressing 17beta-HSD12 670273 1.1.1.64 testosterone 17beta-dehydrogenase (NADP+) HEK-293 cell - 657673, 658172, 658489 1.1.5.3 glycerol-3-phosphate dehydrogenase HEK-293 cell - 760855 1.1.99.24 hydroxyacid-oxoacid transhydrogenase HEK-293 cell mouse homologue expressed in 664967 1.1.99.39 D-2-hydroxyglutarate dehydrogenase HEK-293 cell - 741050 1.11.1.24 thioredoxin-dependent peroxiredoxin HEK-293 cell - 684680 1.13.11.11 tryptophan 2,3-dioxygenase HEK-293 cell - 764267 1.13.11.24 quercetin 2,3-dioxygenase HEK-293 cell HeLa cells contain higher content of pirin protein than normal kidney human epithelial or HEK-293 cells 686336 1.13.11.34 arachidonate 5-lipoxygenase HEK-293 cell - 764451, 765132 1.13.11.52 indoleamine 2,3-dioxygenase HEK-293 cell - 712230, 724912 1.14.11.2 procollagen-proline 4-dioxygenase HEK-293 cell - 673465 1.14.11.29 hypoxia-inducible factor-proline dioxygenase HEK-293 cell - 725596 1.14.11.30 hypoxia-inducible factor-asparagine dioxygenase HEK-293 cell - 725596 1.14.11.4 procollagen-lysine 5-dioxygenase HEK-293 cell - 699120 1.14.11.4 procollagen-lysine 5-dioxygenase HEK-293 cell expression of LH2long and LH2short 659845 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase HEK-293 cell - 744861, 752641 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase HEK-293 cell up-regulation of mRNA and protein after exposure to hypoxia or iron scavengers in vitro. Blocking of hypoxia-inducible factor 1 signaling abrogates the up-regulation 684929 1.14.13.9 kynurenine 3-monooxygenase HEK-293 cell - 742082 1.14.14.23 cholesterol 7alpha-monooxygenase HEK-293 cell - 736800 1.14.14.23 cholesterol 7alpha-monooxygenase HEK-293 cell enzyme expression analysis, increased levels of Cyp7a1/CYP7A1 mRNA in human hepatocytes treated with 1alpha,25-dihydroxyvitamin D3 736169 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase HEK-293 cell - 686694, 702427, 705397 1.14.15.15 cholestanetriol 26-monooxygenase HEK-293 cell - 702407 1.14.15.3 alkane 1-monooxygenase HEK-293 cell - 703239 1.14.16.2 tyrosine 3-monooxygenase HEK-293 cell - 745370 1.14.16.4 tryptophan 5-monooxygenase HEK-293 cell - 687704, 688507 1.14.18.1 tyrosinase HEK-293 cell - 687841 1.14.18.2 CMP-N-acetylneuraminate monooxygenase HEK-293 cell - 701238 1.14.19.1 stearoyl-CoA 9-desaturase HEK-293 cell - 695468 1.17.4.4 vitamin-K-epoxide reductase (warfarin-sensitive) HEK-293 cell - 672776, 672777, 725845, 745877 1.17.4.5 vitamin-K-epoxide reductase (warfarin-insensitive) HEK-293 cell - 725845 1.2.1.105 2-oxoglutarate dehydrogenase system HEK-293 cell The HEK-293 subline E2k-67 shows about 30% reduced KGDHC activity; control line E2k-100 699659 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) HEK-293 cell - 700503, 742751 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) HEK-293 cell infected with Japanese encephalitis virus 699035 1.2.1.13 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) HEK-293 cell - 672334 1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) HEK-293 cell - 673938 1.21.99.4 thyroxine 5'-deiodinase HEK-293 cell - 699169 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) HEK-293 cell - 685576 1.3.5.1 succinate dehydrogenase HEK-293 cell - 700139 1.3.8.1 short-chain acyl-CoA dehydrogenase HEK-293 cell - 712126 1.3.99.23 all-trans-retinol 13,14-reductase HEK-293 cell - 700301 1.3.99.5 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) HEK-293 cell - 740177 1.4.3.3 D-amino-acid oxidase HEK-293 cell - 743062, 763092 1.5.1.2 pyrroline-5-carboxylate reductase HEK-293 cell - 674605 1.5.1.30 flavin reductase (NADPH) HEK-293 cell - 659261 1.5.1.53 methylenetetrahydrofolate reductase (NADPH) HEK-293 cell - 760654 1.5.1.6 formyltetrahydrofolate dehydrogenase HEK-293 cell transformed embryonic kidney cell line HEK-293A 392350 1.5.3.7 L-pipecolate oxidase HEK-293 cell - 742960 1.6.2.2 cytochrome-b5 reductase HEK-293 cell - 742351 1.6.3.1 NAD(P)H oxidase (H2O2-forming) HEK-293 cell - 659626 1.6.5.2 NAD(P)H dehydrogenase (quinone) HEK-293 cell - 713018 1.8.1.6 cystine reductase HEK-293 cell - 743682 1.8.1.9 thioredoxin-disulfide reductase HEK-293 cell - 711283, 711966 1.8.1.9 thioredoxin-disulfide reductase HEK-293 cell HEK-293 cells show low basal levels of TxnRd1 711672 1.8.1.9 thioredoxin-disulfide reductase HEK-293 cell overexpression of TrxR1 inhibits migration of HEK-293 cells 685436 1.8.3.7 formylglycine-generating enzyme HEK-293 cell - 742852 1.8.4.11 peptide-methionine (S)-S-oxide reductase HEK-293 cell - 698124 1.8.98.2 sulfiredoxin HEK-293 cell - 698993, 700520 2.1.1.1 nicotinamide N-methyltransferase HEK-293 cell no expression of NNMT in 687897 2.1.1.137 arsenite methyltransferase HEK-293 cell - 718748, 733451 2.1.1.319 type I protein arginine methyltransferase HEK-293 cell - 756861 2.1.1.320 type II protein arginine methyltransferase HEK-293 cell - 733280, 756139 2.1.1.346 U6 snRNA m6A methyltransferase HEK-293 cell - 744790 2.1.1.348 mRNA m6A methyltransferase HEK-293 cell - 743373, 756405 2.1.1.35 tRNA (uracil54-C5)-methyltransferase HEK-293 cell - 757866 2.1.1.354 [histone H3]-lysine4 N-trimethyltransferase HEK-293 cell - 674513, 703392 2.1.1.355 [histone H3]-lysine9 N-trimethyltransferase HEK-293 cell - 672911, 754061, 755134 2.1.1.356 [histone H3]-lysine27 N-trimethyltransferase HEK-293 cell - 754061 2.1.1.359 [histone H3]-lysine36 N-trimethyltransferase HEK-293 cell - 754105, 754926 2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase HEK-293 cell - 753144 2.1.1.361 [histone H4]-lysine20 N-methyltransferase HEK-293 cell - 719018, 753740 2.1.1.364 [histone H3]-lysine4 N-methyltransferase HEK-293 cell - 758847 2.1.1.45 thymidylate synthase HEK-293 cell additionally transfected with pLGC-hUgi and pLGCX plasmids 692015 2.1.1.57 methyltransferase cap1 HEK-293 cell - 757292 2.1.1.60 calmodulin-lysine N-methyltransferase HEK-293 cell - 735078 2.1.1.67 thiopurine S-methyltransferase HEK-293 cell - 718804 2.1.1.72 site-specific DNA-methyltransferase (adenine-specific) HEK-293 cell - 719373 2.1.1.77 protein-L-isoaspartate(D-aspartate) O-methyltransferase HEK-293 cell - 701664, 702015, 719263 2.1.1.B123 16S rRNA (uridine1369-2'-O)-methyltransferase HEK-293 cell - 757147 2.1.1.B124 16S rRNA (guanine1370-2'-O)-methyltransferase HEK-293 cell - 757147 2.1.1.B125 16S rRNA (guanine1145-2'-O)-methyltransferase HEK-293 cell - 757147 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase HEK-293 cell - 736802 2.3.1.137 carnitine O-octanoyltransferase HEK-293 cell - 718746 2.3.1.15 glycerol-3-phosphate 1-O-acyltransferase HEK-293 cell - 687685, 701623 2.3.1.176 propanoyl-CoA C-acyltransferase HEK-293 cell - 736836 2.3.1.21 carnitine O-palmitoyltransferase HEK-293 cell kidney cell line 672147 2.3.1.225 protein S-acyltransferase HEK-293 cell - 756336 2.3.1.23 1-acylglycerophosphocholine O-acyltransferase HEK-293 cell - 705000, 705001, 735571 2.3.1.250 [Wnt protein] O-palmitoleoyl transferase HEK-293 cell - 733769, 734745 2.3.1.255 N-terminal amino-acid Nalpha-acetyltransferase NatA HEK-293 cell - 702870, 720453 2.3.1.256 N-terminal methionine Nalpha-acetyltransferase NatC HEK-293 cell - 756860 2.3.1.257 N-terminal L-serine Nalpha-acetyltransferase NatD HEK-293 cell - 720835 2.3.1.258 N-terminal methionine Nalpha-acetyltransferase NatE HEK-293 cell - 673832, 740753 2.3.1.259 N-terminal methionine Nalpha-acetyltransferase NatF HEK-293 cell - 735904 2.3.1.299 sphingoid base N-stearoyltransferase HEK-293 cell - 752796, 755995, 757367 2.3.1.32 lysine N-acetyltransferase HEK-293 cell p53 modulation assay 704529 2.3.1.48 histone acetyltransferase HEK-293 cell - 686096, 702497, 702649, 755702 2.3.1.48 histone acetyltransferase HEK-293 cell p53 modulation assay 704529 2.3.1.5 arylamine N-acetyltransferase HEK-293 cell - 672920 2.3.1.50 serine C-palmitoyltransferase HEK-293 cell - 671900, 702434 2.3.1.50 serine C-palmitoyltransferase HEK-293 cell very low SPTLC3 content 674711 2.3.1.57 diamine N-acetyltransferase HEK-293 cell - 687634 2.3.1.57 diamine N-acetyltransferase HEK-293 cell activity of SSAT is increased 28fold in tetracycline-induced cells. Increase in SSAT levels in HEK-293 cells leads to depletion of polyamines and elevation in the enzymatic activities of ornithine decarboxylase and S-adenosylmethionine decarboxylase, suggestive of a compensatory reaction to increased polyamine catabolism. Increased expression of SSAT also leads to DNA damage and G2 arrest 671226 2.3.1.97 glycylpeptide N-tetradecanoyltransferase HEK-293 cell - 487771, 735612 2.3.1.B41 protein-long-chain fatty-acyl-lysine deacylase (NAD+) HEK-293 cell - 757236 2.3.1.B43 protein-lysine desuccinylase (NAD+) HEK-293 cell - 757175 2.3.2.13 protein-glutamine gamma-glutamyltransferase HEK-293 cell - 735910 2.3.2.2 gamma-glutamyltransferase HEK-293 cell - 757548 2.3.2.23 E2 ubiquitin-conjugating enzyme HEK-293 cell - 734357 2.3.2.26 HECT-type E3 ubiquitin transferase HEK-293 cell - 705698, 734247 2.3.2.27 RING-type E3 ubiquitin transferase HEK-293 cell - 734357 2.3.2.31 RBR-type E3 ubiquitin transferase HEK-293 cell - 744784 2.3.2.5 glutaminyl-peptide cyclotransferase HEK-293 cell - 672393 2.3.2.8 arginyltransferase HEK-293 cell - 488021, 760187 2.3.3.1 citrate (Si)-synthase HEK-293 cell - 704788 2.4.1.109 dolichyl-phosphate-mannose-protein mannosyltransferase HEK-293 cell - 674828 2.4.1.17 glucuronosyltransferase HEK-293 cell - 759116 2.4.1.212 hyaluronan synthase HEK-293 cell - 690807, 692996 2.4.1.255 protein O-GlcNAc transferase HEK-293 cell - 735642 2.4.1.255 protein O-GlcNAc transferase HEK-293 cell expression of OGT shows no significant influence on NFkappaB activity 703439 2.4.1.312 protein O-mannose beta-1,4-N-acetylglucosaminyltransferase HEK-293 cell - 726488 2.4.1.313 protein O-mannose beta-1,3-N-acetylgalactosaminyltransferase HEK-293 cell - 726488 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase HEK-293 cell - 757208 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase HEK-293 cell HEK293 controls and HEK cells deleted for GalNAc-T2 or GalNAc-T3 736460 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase HEK-293 cell ppGalNAcT-10 amplified from isolated total RNA 687750 2.4.1.50 procollagen galactosyltransferase HEK-293 cell - 699120, 756226 2.4.1.62 ganglioside galactosyltransferase HEK-293 cell - 757755 2.4.1.65 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase HEK-293 cell - 660797 2.4.1.66 procollagen glucosyltransferase HEK-293 cell - 699120 2.4.1.68 glycoprotein 6-alpha-L-fucosyltransferase HEK-293 cell - 703041, 721723 2.4.2.10 orotate phosphoribosyltransferase HEK-293 cell - 735748 2.4.2.12 nicotinamide phosphoribosyltransferase HEK-293 cell - 760043 2.4.2.26 protein xylosyltransferase HEK-293 cell XT-II mRNA expression is higher than for XT-I. Very low XT-I mRNA expression 702090 2.4.2.30 NAD+ ADP-ribosyltransferase HEK-293 cell - 671265 2.4.2.31 NAD+-protein-arginine ADP-ribosyltransferase HEK-293 cell - 723565, 723579 2.5.1.58 protein farnesyltransferase HEK-293 cell - 704641 2.7.1.1 hexokinase HEK-293 cell - 737798, 758656 2.7.1.107 diacylglycerol kinase (ATP) HEK-293 cell - 675992, 721730 2.7.1.137 phosphatidylinositol 3-kinase HEK-293 cell - 687561 2.7.1.138 ceramide kinase HEK-293 cell - 671750, 671756, 690404 2.7.1.149 1-phosphatidylinositol-5-phosphate 4-kinase HEK-293 cell - 684375 2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase HEK-293 cell - 697230, 738651 2.7.1.23 NAD+ kinase HEK-293 cell - 693013, 760196 2.7.1.24 dephospho-CoA kinase HEK-293 cell - 722282 2.7.1.33 pantothenate kinase HEK-293 cell - 676884 2.7.1.36 mevalonate kinase HEK-293 cell - 662499 2.7.1.40 pyruvate kinase HEK-293 cell - 710047 2.7.1.47 D-ribulokinase HEK-293 cell - 759480 2.7.1.60 N-acylmannosamine kinase HEK-293 cell - 661666, 674638, 728341 2.7.1.67 1-phosphatidylinositol 4-kinase HEK-293 cell - 722802, 758569 2.7.1.68 1-phosphatidylinositol-4-phosphate 5-kinase HEK-293 cell - 641854, 721497, 738106, 738199, 738659 2.7.1.78 polynucleotide 5'-hydroxyl-kinase HEK-293 cell - 751906, 762248 2.7.1.91 sphingosine kinase HEK-293 cell - 685792 2.7.10.1 receptor protein-tyrosine kinase HEK-293 cell - 662679, 691714, 693727, 723560 2.7.10.2 non-specific protein-tyrosine kinase HEK-293 cell - 690338, 738650 2.7.11.1 non-specific serine/threonine protein kinase HEK-293 cell - 662260, 671945, 693189, 707574, 739247 2.7.11.10 IkappaB kinase HEK-293 cell - 662155, 691616, 693060, 693461, 694833, 702333, 704348, 704476 2.7.11.10 IkappaB kinase HEK-293 cell embryonic kidney cell line 662357 2.7.11.11 cAMP-dependent protein kinase HEK-293 cell - 662153, 662206, 662212, 662393, 761464, 762271 2.7.11.11 cAMP-dependent protein kinase HEK-293 cell embryonic kidney cell 661013 2.7.11.12 cGMP-dependent protein kinase HEK-293 cell - 661456, 661575, 693846, 694559 2.7.11.13 protein kinase C HEK-293 cell - 662219, 702383, 703683, 724170, 737786, 760634 2.7.11.15 beta-adrenergic-receptor kinase HEK-293 cell - 662153, 672951, 677232, 685121, 688125, 739031 2.7.11.16 G-protein-coupled receptor kinase HEK-293 cell - 685121, 705737 2.7.11.17 Ca2+/calmodulin-dependent protein kinase HEK-293 cell - 665701, 693725, 760861 2.7.11.18 myosin-light-chain kinase HEK-293 cell - 710379 2.7.11.21 polo kinase HEK-293 cell - 705986, 727149 2.7.11.22 cyclin-dependent kinase HEK-293 cell - 663933, 680759, 694491, 723656 2.7.11.24 mitogen-activated protein kinase HEK-293 cell - 701309 2.7.11.24 mitogen-activated protein kinase HEK-293 cell a plasmid encoding Flag-JNK1 is transformed into HEK-293 cells expressing the melanocortin receptor type 4 706080 2.7.11.25 mitogen-activated protein kinase kinase kinase HEK-293 cell - 665601, 680887, 681764, 681911, 740696 2.7.11.25 mitogen-activated protein kinase kinase kinase HEK-293 cell embryonic kidney cell line 665804 2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase HEK-293 cell - 644986 2.7.11.8 Fas-activated serine/threonine kinase HEK-293 cell - 761934 2.7.11.9 Goodpasture-antigen-binding protein kinase HEK-293 cell - 661708 2.7.12.1 dual-specificity kinase HEK-293 cell - 703667 2.7.4.10 nucleoside-triphosphate-adenylate kinase HEK-293 cell - 737551 2.7.4.2 phosphomevalonate kinase HEK-293 cell endogenously expressed human phosphomevalonate kinase and overexpressed human phosphomevalonate kinase 662590 2.7.4.21 inositol-hexakisphosphate 5-kinase HEK-293 cell - 662355, 722717, 762284 2.7.4.6 nucleoside-diphosphate kinase HEK-293 cell - 693134 2.7.7.12 UDP-glucose-hexose-1-phosphate uridylyltransferase HEK-293 cell - 760856 2.7.7.19 polynucleotide adenylyltransferase HEK-293 cell - 762043 2.7.7.4 sulfate adenylyltransferase HEK-293 cell - 723546 2.7.7.40 D-ribitol-5-phosphate cytidylyltransferase HEK-293 cell - 760903 2.7.7.52 RNA uridylyltransferase HEK-293 cell - 723763 2.7.7.6 DNA-directed RNA polymerase HEK-293 cell - 705139 2.7.7.8 polyribonucleotide nucleotidyltransferase HEK-293 cell - 723310 2.7.8.1 ethanolaminephosphotransferase HEK-293 cell - 761663 2.7.8.2 diacylglycerol cholinephosphotransferase HEK-293 cell - 761663 2.7.8.27 sphingomyelin synthase HEK-293 cell - 690656, 691046, 707360 2.7.8.29 L-serine-phosphatidylethanolamine phosphatidyltransferase HEK-293 cell - 693711 2.7.8.5 CDP-diacylglycerol-glycerol-3-phosphate 1-phosphatidyltransferase HEK-293 cell - 739659 2.8.1.2 3-mercaptopyruvate sulfurtransferase HEK-293 cell - 762435 2.8.2.5 chondroitin 4-sulfotransferase HEK-293 cell - 760531 3.1.1.116 sn-1-specific diacylglycerol lipase HEK-293 cell - 761578 3.1.1.13 sterol esterase HEK-293 cell - 715834 3.1.1.23 acylglycerol lipase HEK-293 cell - 730424 3.1.1.6 acetylesterase HEK-293 cell lower expression level than in Hep-G2 cells as revealed by Northern blot and quantitative RT-PCR, serum-induced inhibition of gene expression (quantitative RT-PCR, FACS, reporter gene assay) 696095 3.1.1.7 acetylcholinesterase HEK-293 cell - 691246, 714704 3.1.1.89 protein phosphatase methylesterase-1 HEK-293 cell - 732080, 732140 3.1.2.12 S-formylglutathione hydrolase HEK-293 cell - 751775 3.1.2.22 palmitoyl[protein] hydrolase HEK-293 cell - 23910 3.1.21.10 crossover junction endodeoxyribonuclease HEK-293 cell - 714118 3.1.26.3 ribonuclease III HEK-293 cell - 691106 3.1.26.4 ribonuclease H HEK-293 cell - 751749 3.1.26.4 ribonuclease H HEK-293 cell embryonal kidney cell line, high level in enzyme type 1 activity, low level in enzyme type 2 activity 655447 3.1.3.16 protein-serine/threonine phosphatase HEK-293 cell - 663946, 664932, 666352, 666403, 678133, 680788, 692269 3.1.3.32 polynucleotide 3'-phosphatase HEK-293 cell - 751906 3.1.3.4 phosphatidate phosphatase HEK-293 cell - 663994, 681760, 714316 3.1.3.4 phosphatidate phosphatase HEK-293 cell LPP3 679860 3.1.3.46 fructose-2,6-bisphosphate 2-phosphatase HEK-293 cell - 730008 3.1.3.48 protein-tyrosine-phosphatase HEK-293 cell - 693029, 694163, 707975, 750022 3.1.3.5 5'-nucleotidase HEK-293 cell - 652095, 749946, 752251 3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase HEK-293 cell - 692556, 694495, 694916 3.1.3.95 phosphatidylinositol-3,5-bisphosphate 3-phosphatase HEK-293 cell - 665651, 750410 3.1.4.11 phosphoinositide phospholipase C HEK-293 cell - 668227, 682121, 694268, 751930 3.1.4.12 sphingomyelin phosphodiesterase HEK-293 cell - 730294, 751328 3.1.4.35 3',5'-cyclic-GMP phosphodiesterase HEK-293 cell - 680637 3.1.4.39 alkylglycerophosphoethanolamine phosphodiesterase HEK-293 cell LysoPLD activity is determined in culture medium from control cells or cells expressing V5-autotaxin (ATX) 681769 3.1.4.4 phospholipase D HEK-293 cell - 664162, 681534, 707551, 709038, 709597, 709606, 749455 3.1.4.4 phospholipase D HEK-293 cell isozymes PLD1 and PLD2 710407 3.1.4.46 glycerophosphodiester phosphodiesterase HEK-293 cell - 694209 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase HEK-293 cell - 685046, 688125 3.1.6.2 steryl-sulfatase HEK-293 cell - 705709 3.1.6.2 steryl-sulfatase HEK-293 cell human embryonic kidney cells 691323 3.1.6.4 N-acetylgalactosamine-6-sulfatase HEK-293 cell - 694099 3.2.1.113 mannosyl-oligosaccharide 1,2-alpha-mannosidase HEK-293 cell - 751118 3.2.1.166 heparanase HEK-293 cell - 714343 3.2.1.169 protein O-GlcNAcase HEK-293 cell - 702128 3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing) HEK-293 cell - 716189, 728341 3.2.1.209 endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase HEK-293 cell - 754232 3.2.1.24 alpha-mannosidase HEK-293 cell - 678045 3.2.1.52 beta-N-acetylhexosaminidase HEK-293 cell - 696118 3.3.2.10 soluble epoxide hydrolase HEK-293 cell - 709061, 709447 3.4.11.2 membrane alanyl aminopeptidase HEK-293 cell - 683431, 699428 3.4.11.3 cystinyl aminopeptidase HEK-293 cell - 683431 3.4.11.4 tripeptide aminopeptidase HEK-293 cell - 679995 3.4.13.18 cytosol nonspecific dipeptidase HEK-293 cell - 755247 3.4.14.10 tripeptidyl-peptidase II HEK-293 cell - 679643, 679995, 731223 3.4.15.1 peptidyl-dipeptidase A HEK-293 cell stably transfected with full-length ACE2 679876 3.4.17.12 carboxypeptidase M HEK-293 cell - 683685, 732121 3.4.17.23 angiotensin-converting enzyme 2 HEK-293 cell - 668550 3.4.17.24 tubulin-glutamate carboxypeptidase HEK-293 cell - 731634 3.4.21.104 mannan-binding lectin-associated serine protease-2 HEK-293 cell - 709344 3.4.21.106 hepsin HEK-293 cell - 707437 3.4.21.108 HtrA2 peptidase HEK-293 cell - 667167, 667480, 668876, 669278, 669282, 699486 3.4.21.109 matriptase HEK-293 cell - 673572, 717839 3.4.21.112 site-1 protease HEK-293 cell - 718062 3.4.21.22 coagulation factor IXa HEK-293 cell - 709724 3.4.21.26 prolyl oligopeptidase HEK-293 cell - 683344, 683389, 732303 3.4.21.45 complement factor I HEK-293 cell transfected with mutant and wild-type forms of complement factor I 683892 3.4.21.53 Endopeptidase La HEK-293 cell wild-type and HtrA2 knock-down HEK293T cells 731762 3.4.21.6 coagulation factor Xa HEK-293 cell - 754844 3.4.21.61 Kexin HEK-293 cell - 707332, 732728 3.4.21.75 Furin HEK-293 cell - 669214, 680696, 710165, 732774 3.4.21.76 Myeloblastin HEK-293 cell - 664960 3.4.21.B25 PACE4 proprotein convertase HEK-293 cell - 671865, 673909 3.4.21.B26 proprotein convertase 5 HEK-293 cell - 675967 3.4.21.B45 kallikrein 14 HEK-293 cell - 731398 3.4.22.15 cathepsin L HEK-293 cell - 651159, 713582 3.4.22.34 Legumain HEK-293 cell - 696499 3.4.22.40 bleomycin hydrolase HEK-293 cell - 717821 3.4.22.53 calpain-2 HEK-293 cell - 709540 3.4.22.55 caspase-2 HEK-293 cell - 711715 3.4.22.56 caspase-3 HEK-293 cell - 647619, 647629, 701309 3.4.22.57 caspase-4 HEK-293 cell - 677484 3.4.22.60 caspase-7 HEK-293 cell - 670408, 717785 3.4.22.61 caspase-8 HEK-293 cell - 647434, 665924, 708496, 718144 3.4.22.B70 SENP1 peptidase HEK-293 cell - 754169 3.4.23.46 memapsin 2 HEK-293 cell - 711906, 734456, 753489 3.4.23.46 memapsin 2 HEK-293 cell stably expressing human BACE1 enzyme, used for inhibition assay 683238 3.4.23.B1 napsin HEK-293 cell - 752689 3.4.23.B1 napsin HEK-293 cell re-expression of napsin A in tumorigenic HEK293 kidney cell line, reduced capacity for anchorage-independent growth observed 683839 3.4.23.B24 signal peptide peptidase HEK-293 cell - 753201, 753429, 754400 3.4.24.11 neprilysin HEK-293 cell both staurosporine-stimulated caspase-3 activation, p53 and neprilysin expression and activity are not affected by over-expression or depletion of presenilin complex component TMP21 695993 3.4.24.15 thimet oligopeptidase HEK-293 cell - 683813, 753583 3.4.24.15 thimet oligopeptidase HEK-293 cell EP24.15 colocalizes with calmodulin in the cytosol of resting HEK293 cells 708478 3.4.24.18 meprin A HEK-293 cell - 685446 3.4.24.56 insulysin HEK-293 cell - 754114 3.4.24.61 nardilysin HEK-293 cell mRNA isolated from 719245 3.4.24.71 endothelin-converting enzyme 1 HEK-293 cell - 683416, 683439, 734268, 752727 3.4.24.79 pappalysin-1 HEK-293 cell - 754115 3.4.24.81 ADAM10 endopeptidase HEK-293 cell - 644072, 697848, 708492, 719416, 720832, 733247, 734663, 735127, 753122, 755427 3.4.24.81 ADAM10 endopeptidase HEK-293 cell embryonic wild type cell line and overexpressing ADAM10 639004 3.4.24.86 ADAM 17 endopeptidase HEK-293 cell - 681665, 735127, 752817, 755446 3.4.24.B18 m-AAA protease HEK-293 cell - 753920 3.4.25.1 proteasome endopeptidase complex HEK-293 cell - 684965, 712705 3.5.1.23 ceramidase HEK-293 cell - 718697 3.5.1.60 N-(long-chain-acyl)ethanolamine deacylase HEK-293 cell - 752811, 753248 3.5.1.88 peptide deformylase HEK-293 cell - 675061 3.5.1.98 histone deacetylase HEK-293 cell - 696048, 704641, 712434 3.5.4.1 cytosine deaminase HEK-293 cell - 718465 3.5.4.37 double-stranded RNA adenine deaminase HEK-293 cell - 720953, 721098, 757225 3.6.1.59 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase HEK-293 cell - 716801 3.6.1.62 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase HEK-293 cell - 716207, 716218 3.6.4.6 vesicle-fusing ATPase HEK-293 cell - 669490 3.6.4.6 vesicle-fusing ATPase HEK-293 cell HsPex6p 669490 3.6.4.B10 chaperonin ATPase (protein-folding, protecting from aggregation, protein stabilizing) HEK-293 cell - 757168 3.6.5.1 heterotrimeric G-protein GTPase HEK-293 cell - 676909, 697230, 701012 3.6.5.2 small monomeric GTPase HEK-293 cell - 670240, 696514 4.1.1.17 ornithine decarboxylase HEK-293 cell - 696087, 696119 4.1.1.28 aromatic-L-amino-acid decarboxylase HEK-293 cell - 716342 4.1.1.33 diphosphomevalonate decarboxylase HEK-293 cell - 653248 4.1.1.50 adenosylmethionine decarboxylase HEK-293 cell - 702137 4.1.1.90 peptidyl-glutamate 4-carboxylase HEK-293 cell - 699860, 701214 4.1.2.13 fructose-bisphosphate aldolase HEK-293 cell - 748764 4.1.2.27 sphinganine-1-phosphate aldolase HEK-293 cell - 681269, 682517, 713688, 726675 4.2.1.11 phosphopyruvate hydratase HEK-293 cell - 703010 4.2.1.2 fumarate hydratase HEK-293 cell - 706404 4.2.1.3 aconitate hydratase HEK-293 cell - 663958, 666706, 696168 4.3.2.9 gamma-glutamylcyclotransferase HEK-293 cell - 705761 4.4.1.20 leukotriene-C4 synthase HEK-293 cell - 664161, 681027 4.4.1.5 lactoylglutathione lyase HEK-293 cell - 694142 4.6.1.1 adenylate cyclase HEK-293 cell - 664044, 681009, 693116, 695074, 708403, 709018, 710590 4.6.1.1 adenylate cyclase HEK-293 cell AC2, AC9 682112 4.6.1.1 adenylate cyclase HEK-293 cell AC8 682285 4.6.1.1 adenylate cyclase HEK-293 cell HEK-hD1, HEK-293 cells transiently transfected with human D1 dopamine receptor 693772 4.6.1.19 ribonuclease T2 HEK-293 cell - 751115 4.6.1.2 guanylate cyclase HEK-293 cell - 729139 5.1.3.14 UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) HEK-293 cell - 716189 5.1.3.17 heparosan-N-sulfate-glucuronate 5-epimerase HEK-293 cell - 662196 5.1.99.4 alpha-methylacyl-CoA racemase HEK-293 cell - 727330 5.2.1.8 peptidylprolyl isomerase HEK-293 cell - 693136, 705715, 747512 5.3.99.3 prostaglandin-E synthase HEK-293 cell - 670732 5.6.1.1 microtubule-severing ATPase HEK-293 cell - 696957 5.6.1.2 dynein ATPase HEK-293 cell - 669418 5.6.1.5 proteasome ATPase HEK-293 cell - 751667, 751695, 752040 5.6.1.6 channel-conductance-controlling ATPase HEK-293 cell - 751065 5.6.2.1 DNA topoisomerase HEK-293 cell - 747698, 750702 5.6.2.2 DNA topoisomerase (ATP-hydrolysing) HEK-293 cell - 715868, 728231 5.6.2.3 DNA 5'-3' helicase HEK-293 cell - 756521 6.1.1.14 glycine-tRNA ligase HEK-293 cell - 745876 6.1.1.19 arginine-tRNA ligase HEK-293 cell - 672090, 745338 6.1.1.4 leucine-tRNA ligase HEK-293 cell - 727276, 744654 6.1.1.6 lysine-tRNA ligase HEK-293 cell - 663247 6.2.1.3 long-chain-fatty-acid-CoA ligase HEK-293 cell - 726883 6.2.1.45 E1 ubiquitin-activating enzyme HEK-293 cell - 735013 6.3.1.1 aspartate-ammonia ligase HEK-293 cell - 693193 6.3.1.4 aspartate-ammonia ligase (ADP-forming) HEK-293 cell - 693193 6.3.4.10 biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase HEK-293 cell - 715997, 715999 6.3.4.21 nicotinate phosphoribosyltransferase HEK-293 cell exogenously added nicotinic acid (1-10 microM) leads to increase in basal total NAD++ level (revealed by ESI-MS) in a dose-dependent manner and to NaAD+ accumulation which are reduced by siRNA-based knock-down of endogenous NAPRT, knock-down does not affect basal NAD++ levels (503 +/-104 microM) in absence of exogenous nicotinic acid, exogenously added nicotinic acid decreases oxidative cytotoxicity (by 30-50 microM hydrogen peroxide) through elevated NAD+ levels mediated by NAPRT activity as revealed by siRNA-based knock-down of NAPRT 680797 6.3.4.21 nicotinate phosphoribosyltransferase HEK-293 cell weak expression 745944 6.3.4.3 formate-tetrahydrofolate ligase HEK-293 cell - 701402 6.3.4.5 argininosuccinate synthase HEK-293 cell - 704509 6.5.1.1 DNA ligase (ATP) HEK-293 cell - 1938 6.5.1.8 3'-phosphate/5'-hydroxy nucleic acid ligase HEK-293 cell - 748760 7.1.2.2 H+-transporting two-sector ATPase HEK-293 cell - 720941 7.2.2.10 P-type Ca2+ transporter HEK-293 cell - 697167 7.2.2.14 P-type Mg2+ transporter HEK-293 cell - 699121 7.2.2.19 H+/K+-exchanging ATPase HEK-293 cell - 698979 7.2.2.8 P-type Cu+ transporter HEK-293 cell - 751286 7.2.2.9 P-type Cu2+ transporter HEK-293 cell ATP7A and ATP7B 701335 7.6.2.2 ABC-type xenobiotic transporter HEK-293 cell - 210399, 210400, 210401, 210402, 747041, 748763 7.6.2.2 ABC-type xenobiotic transporter HEK-293 cell 293 human embryonic kidney cells and Madin-darby canine kidney II cells transfected with a MRP5 cDNA construct 210395 7.6.2.4 ABC-type fatty-acyl-CoA transporter HEK-293 cell - 750514