3.4.19.12 Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal) a 76-residue protein attached to proteins as an intracellular targeting signal - 3.4.19.12 Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal) Cys90 and His161 are involved in catalytic rate enhancement 36456 3.4.19.12 Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal) UCH-L1 is a neuro-specific multifunctional enzyme, deubiquinating, ubiquitinyl ligase, and also stabilizing ubiquitin monomers, C90 is the active site residue 663891