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Gene ontology
Version 2014-12-22
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Details for isocitrate dehydrogenase (NADP+) activity
1.1.1.42
Gene ontology ID
GO:0004450
Definition
Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+
Synonyms
1. dual-cofactor-specific isocitrate dehydrogenase activity
2. isocitrate (NADP) dehydrogenase activity
3. isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity
4. isocitrate dehydrogenase (NADP) activity
5. isocitrate dehydrogenase (NADP-dependent) activity
6. isocitrate:NADP+ oxidoreductase (decarboxylating)
7. NADP isocitric dehydrogenase activity
8. NADP(+)-ICDH activity
9. NADP(+)-IDH activity
10. NADP(+)-linked isocitrate dehydrogenase activity
11. NADP-dependent isocitrate dehydrogenase activity
12. NADP-dependent isocitric dehydrogenase activity
13. NADP-linked isocitrate dehydrogenase activity
14. NADP-specific isocitrate dehydrogenase activity
15. triphosphopyridine nucleotide-linked isocitrate dehydrogenase activity
References
1. EC 1.1.1.42
2. MetaCyc ISOCITDEH-RXN
3. Reactome: R-HSA-389540 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+"
4. Reactome: R-HSA-389550 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+"
5. Reactome: R-HSA-450984 "isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2]"
6. RHEA: 19629
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