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Literature summary extracted from

  • Ferizhendi, K.; Simon, P.; Pelosi, L.; Sechet, E.; Arulanandam, R.; Chehade, M.; Rey, M.; Onal, D.; Flandrin, L.; Chreim, R.; Faivre, B.; Chau-Duy-Tam Vo, S.; Arias-Cartin, R.; Barras, F.; Fontecave, M.; Bouveret, E.; Lombard, M.; Pierrel, F.
    An organic O donor for biological hydroxylation reactions (2024), Proc. Natl. Acad. Sci. USA, 121, e2321242121.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.97.1.15 a 2-(all-trans-polyprenyl)phenol + prephenate + acceptor Escherichia coli
-
 a 3-(all-trans-polyprenyl)benzene-1,2-diol + 3-phenyl-2-oxopropanoate + CO2 + reduced acceptor
-
 ?
1.97.1.15 a 2-methoxy-6-(all-trans-polyprenyl)phenol + prephenate + acceptor Escherichia coli
-
 a 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol + 3-phenyl-2-oxopropanoate + CO2 + reduced acceptor
-
 ?
1.97.1.15 a 5-methoxy-2-methyl-3-(all-trans-polyprenyl)benzene-1,4-diol + prephenate + acceptor Escherichia coli
-
 a 3-demethylubiquinol + 3-phenyl-2-oxopropanoate + CO2 + reduced acceptor
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.97.1.15 Escherichia coli P45527 AND P45475 P45527: ubiquinone biosynthesis protein UbiU, P45475: ubiquinone biosynthesis protein UbiV; substrain MG1655
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.97.1.15 a 2-(all-trans-polyprenyl)phenol + prephenate + acceptor
-
 Escherichia coli a 3-(all-trans-polyprenyl)benzene-1,2-diol + 3-phenyl-2-oxopropanoate + CO2 + reduced acceptor
-
 ?
1.97.1.15 a 2-methoxy-6-(all-trans-polyprenyl)phenol + prephenate + acceptor
-
 Escherichia coli a 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol + 3-phenyl-2-oxopropanoate + CO2 + reduced acceptor
-
 ?
1.97.1.15 a 5-methoxy-2-methyl-3-(all-trans-polyprenyl)benzene-1,4-diol + prephenate + acceptor
-
 Escherichia coli a 3-demethylubiquinol + 3-phenyl-2-oxopropanoate + CO2 + reduced acceptor
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.97.1.15 UbiUV
-
 Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
1.97.1.15 4Fe-4S-center
-
 Escherichia coli

General Information

EC Number General Information Comment Organism
1.97.1.15 metabolism the enzyme catalyses three hydroxylation reactions in the oxygen-independent pathway for ubiquinone biosynthesis Escherichia coli