Literature summary extracted from

Sasaki, M.; Jojima, T.; Inui, M.; Yukawa, H.
Xylitol production by recombinant Corynebacterium glutamicum under oxygen deprivation (2009), Appl. Microbiol. Biotechnol., 86, 1057-1066.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.1.1.307	expression of single-site mutant xylose reductase from Candida tenuis (CtXR (K274R)) results in recombinant Corynebacterium glutamicum strain CtXR4 that produces 26.5 g/l xylitol at 3.1 g/l*h. To eliminate possible formation of toxic intracellular xylitol phosphate, genes encoding xylulokinase (XylB) and phosphoenolpyruvate-dependent fructose phosphotransferase (PTSfru) are disrupted to yield strain CtXR7	Yamadazyma tenuis

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.307	Yamadazyma tenuis	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.307	D-xylose + NADH + H+	dual (NADH and NADPH) coenzyme specificity	Yamadazyma tenuis	xylitol + NAD+	-	?
1.1.1.307	D-xylose + NADPH + H+	dual (NADH and NADPH) coenzyme specificity	Yamadazyma tenuis	xylitol + NADP+	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.1.1.307	CtXR	-	Yamadazyma tenuis

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.1.307	NADH	dual (NADH and NADPH) coenzyme specificity	Yamadazyma tenuis
1.1.1.307	NADPH	dual (NADH and NADPH) coenzyme specificity	Yamadazyma tenuis

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Release 2023.1 (January 2023)