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Literature summary extracted from

  • van Dinten, L.C.; Rensen, S.; Gorbalenya, A.E.; Snijder, E.J.
    Proteolytic processing of the open reading frame 1b-encoded part of arterivirus replicase is mediated by nsp4 serine protease and Is essential for virus replication (1999), J. Virol., 73, 2027-2037.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.21.114
-
equine arteritis virus

Protein Variants

EC Number Protein Variants Comment Organism
3.4.21.114 S1184I no cleavage between nsp9 and nsp10 equine arteritis virus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.114 additional information equine arteritis virus enzyme is the main viral protease ?
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?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.114 equine arteritis virus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.114 arterivirus replicase ORF1b + H2O protein is processed by nsp4 serine protease at the following sites: nsp9/10 i.e. p80/p50, cleavage occurs between Glu2370 and Ser, nsp10/11 i.e. p50/p26, cleavage occurs between Gln2837 and Ser, nsp11/12 i.e. nsp26/p12, cleavage between Glu3056 and Gly equine arteritis virus ?
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?
3.4.21.114 additional information enzyme is the main viral protease equine arteritis virus ?
-
?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.114 nsp4
-
equine arteritis virus
3.4.21.114 nsp4 serine protease
-
equine arteritis virus
3.4.21.114 nsp4SP
-
equine arteritis virus