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Literature summary extracted from

  • MacDonald, M.J.; Brown, L.J.
    Calcium activation of mitochondrial glycerol phosphate dehydrogenase restudied (1996), Arch. Biochem. Biophys., 326, 79-84.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.5.3
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.5.3 0.4
-
 glycerol 3-phosphate enzyme from testis and pancreatic islets, in presence of saturating concentrations of free Ca2+ Rattus norvegicus
1.1.5.3 2.5
-
 glycerol 3-phosphate enzyme from pancreatic islets, in absence of free calcium Rattus norvegicus
1.1.5.3 3.2
-
 glycerol 3-phosphate enzyme from testis in absence of free calcium Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.5.3 mitochondrion inner mitochondrial membrane. The mature protein has three transmembrane helices. The first membrane-spanning region coincides with the FAD site and thus this site is placed within the membrane. The calcium-binding region lies outside the membrane exposed to the cytosolic environment Rattus norvegicus 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.1.5.3 Ca2+ activates Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.5.3 sn-glycerol 3-phosphate + acceptor Rattus norvegicus key enzyme of the glycerol phosphate shuttle glycerone phosphate + reduced acceptor
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.5.3 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.5.3 pancreas
-
 Rattus norvegicus
-
1.1.5.3 testis
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.5.3 sn-glycerol 3-phosphate + acceptor key enzyme of the glycerol phosphate shuttle Rattus norvegicus glycerone phosphate + reduced acceptor
-
 ?