Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Mus musculus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q80YD1 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
liver | low expression level | Mus musculus | - |
muscle | - |
Mus musculus | - |
spleen | - |
Mus musculus | - |
testis | high expression level | Mus musculus | - |
thymus | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
Supv3L1 | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | furing development, expression of Supv3L1 begins at the blastocyst stage, becomes widespread and strong in all fetal tissues and cell types, and continues during postnatal growth. Supv3L1 is an developmentally regulated gene, which continues to be expressed in all mature tissues, particularly the rapidly proliferating cells of testes, but also in the brain and sensory organs | up |
General Information | Comment | Organism |
---|---|---|
malfunction | conditional ablation of Supv3L1 in adult mice leads to premature aging phenotypes including loss of muscle mass and adipose tissue and severe skin abnormalities | Mus musculus |
physiological function | plays a critical role in the mitochondrial RNA surveillance and degradation machinery | Mus musculus |