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Literature summary for 3.6.4.13 extracted from

  • Paul, E.; Kielbasinski, M.; Sedivy, J.M.; Murga-Zamalloa, C.; Khanna, H.; Klysik, J.E.
    Widespread expression of the Supv3L1 mitochondrial RNA helicase in the mouse (2010), Transgenic Res., 19, 691-701.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.4.13

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
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 Mus musculus 5739
-

Organism

Organism UniProt Comment Textmining
Mus musculus Q80YD1
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-
liver low expression level Mus musculus
-
muscle
-
 Mus musculus
-
spleen
-
 Mus musculus
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testis high expression level Mus musculus
-
thymus
-
 Mus musculus
-

Synonyms

Synonyms Comment Organism
Supv3L1
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus furing development, expression of Supv3L1 begins at the blastocyst stage, becomes widespread and strong in all fetal tissues and cell types, and continues during postnatal growth. Supv3L1 is an developmentally regulated gene, which continues to be expressed in all mature tissues, particularly the rapidly proliferating cells of testes, but also in the brain and sensory organs up

General Information

General Information Comment Organism
malfunction conditional ablation of Supv3L1 in adult mice leads to premature aging phenotypes including loss of muscle mass and adipose tissue and severe skin abnormalities Mus musculus
physiological function plays a critical role in the mitochondrial RNA surveillance and degradation machinery Mus musculus