Crystallization (Comment) | Organism |
---|---|
in complex with interferon-stimulated gene product 15 proteins from different species | Severe acute respiratory syndrome-related coronavirus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Severe acute respiratory syndrome-related coronavirus | P0C6X7 | human, i.e. SARS-CoV | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
proISG + H2O | i.e. proenzyme of interferon-stimulated gene product 15 | Severe acute respiratory syndrome-related coronavirus | ? | - |
? |
General Information | Comment | Organism |
---|---|---|
physiological function | SARS-CoV and MERS-CoV PLpros are both capable of fully processing proISG15 from human, mouse, camel and bat within 60 minutes. SARS PLpro is also able to fully process proISG15 from sheep and shrew within that same time but it has little to no activity against jackfish proISG15 | Severe acute respiratory syndrome-related coronavirus |