Organism | UniProt | Comment | Textmining |
---|---|---|---|
Severe acute respiratory syndrome coronavirus 2 | MN908947 | i.e. SARS-CoV-2 | - |
Synonyms | Comment | Organism |
---|---|---|
Mpro | - |
Severe acute respiratory syndrome coronavirus 2 |
SARS-CoV-2 main protease | - |
Severe acute respiratory syndrome coronavirus 2 |
General Information | Comment | Organism |
---|---|---|
drug target | the use of the deep learning platform Deep Docking in conjunction with a docking program allows rapid estimation of docking scores for 1.3 billion chemical structures into an active site of novel SARS-CoV-2 Mpro. The candidate inhibitors in the top-1000 hit list are chemically diverse, exhibit superior docking scores compared to known protease inhibitors. The structures of the identified compounds are made publicly available should facilitate efforts in rapid development of suitable drug candidates against COVID-19 | Severe acute respiratory syndrome coronavirus 2 |