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Literature summary for 3.4.22.69 extracted from

  • Lee, T.; Cherney, M.M.; Liu, J.; James, K.E.; Powers, J.C.; Eltis, L.D.; James, M.N.
    Crystal structures reveal an induced-fit binding of a substrate-like aza-peptide epoxide to SARS coronavirus main peptidase (2007), J. Mol. Biol., 366, 916-932.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging-drop vapor-diffusion method. Crystal structure of the enzyme at a resolution of 1.82 A, in space group P21 at pH 6.0. Two crystal structures of Mpro having an additional Ala at the N terminus of each protomer (M+A(-1)pro), both at a resolution of 2.00 A, in space group P43212: one unbound and one bound by a substrate-like aza-peptide epoxide Severe acute respiratory syndrome-related coronavirus

Organism

Organism UniProt Comment Textmining
Severe acute respiratory syndrome-related coronavirus
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Synonyms

Synonyms Comment Organism
SARS coronavirus main peptidase
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Severe acute respiratory syndrome-related coronavirus