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Literature summary for 3.4.22.53 extracted from

  • Wang, H.C.; Huang, Y.S.; Ho, C.C.; Jeng, J.C.; Shih, H.M.
    SUMO modification modulates the activity of calpain-2 (2009), Biochem. Biophys. Res. Commun., 384, 444-449.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
K390R overexpression of K390R mutant fails to increase the calpain activity since sumoylation at K390 is important for calpain-2 activity Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
side-chain modification calpain-2 is small ubiquitin-like modifier-modified at lysine residue 390, sumoylation is important for calpain-2 activity Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
casein + H2O
-
Homo sapiens ?
-
?

General Information

General Information Comment Organism
physiological function calpain-2 is involved in cell motility Homo sapiens