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Literature summary for 3.4.22.53 extracted from

  • Nuzzi, P.A.; Senetar, M.A.; Huttenlocher, A.
    Asymmetric localization of calpain 2 during neutrophil chemotaxis (2007), Mol. Biol. Cell, 18, 795-805.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens catalytic activity of calpain is required to limit pseudopod formation in the direction of chemoattractant and for efficient chemotaxis. Calpain 2 is a novel component of the frontness signal that promotes polarization during chemotaxis ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
HL-60 cell calpain 2 localizes to GM-3-rich lipid rafts at the leading edge Homo sapiens
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neutrophil primary neutrophil Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information catalytic activity of calpain is required to limit pseudopod formation in the direction of chemoattractant and for efficient chemotaxis. Calpain 2 is a novel component of the frontness signal that promotes polarization during chemotaxis Homo sapiens ?
-
 ?