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Literature summary for 3.4.22.53 extracted from

  • Raynaud, F.; Marcilhac, A.; Chebli, K.; Benyamin, Y.; Rossel, M.
    Calpain 2 expression pattern and sub-cellular localization during mouse embryogenesis (2008), Int. J. Dev. Biol., 52, 383-388.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm from ES cells and the 8-cell stage to late neurulation stages, CAPN2 is expressed in the cytoplasm and nuclear compartments Mus musculus 5737
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nucleus from ES cells and the 8-cell stage to late neurulation stages, CAPN2 is expressed in the cytoplasm and nuclear compartments, with a clear co-localisation with chromatin. Nuclear localization was associated either with active cell mitosis in embryonic stem cells and early developmental stages or with precursor cells later during organogenesis Mus musculus 5634
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus CAPN2 may represent a key factor in development from the first cell division ?
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?

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
chondrocyte
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Mus musculus
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embryo analysis from E8.5 to 14.5 stages indicates high levels of capn2 expression in the nervous system, heart and mesodermal tissues. Up-regulation is maintained during later developmental stages in proliferating cells and in precursor cells involved in muscle (myoblasts) or bone formation (chondrocytes). At later developmental stages, elevated mRNA levels coincide with CAPN2 nuclear localization in these cell types, while differentiated cells maintain cytoplasmic expression Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information CAPN2 may represent a key factor in development from the first cell division Mus musculus ?
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?

Synonyms

Synonyms Comment Organism
CAPN2
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Mus musculus