Activating Compound | Comment | Organism | Structure |
---|---|---|---|
TNF-alpha | activates cytosolic enzyme | Oryctolagus cuniculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzyloxycarbonyl-Leu-Leu-leucinal | - |
Oryctolagus cuniculus | |
benzyloxycarbonyl-Leu-Leu-phenylalaninal | - |
Oryctolagus cuniculus | |
benzyloxycarbonyl-Leu-Leu-Tyr diazomethyl ketone | - |
Oryctolagus cuniculus | |
benzyloxycarbonyl-Leu-norleucinal | - |
Oryctolagus cuniculus | |
E-64 | i.e. trans-epoxysuccinyl-L-leucylamido-(4-guanido)butane | Oryctolagus cuniculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Oryctolagus cuniculus | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
IkappaBalpha + H2O | Oryctolagus cuniculus | a parallel pathway that degrades IkappaBalpha and activates NF-kappaB activation independently of the ubiquitin-proteasome pathway | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skeletal muscle | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Boc-Leu-Met-7-amino-4-chloromethylcoumarin | - |
Oryctolagus cuniculus | ? | - |
? | |
casein + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
IkappaBalpha + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
IkappaBalpha + H2O | a parallel pathway that degrades IkappaBalpha and activates NF-kappaB activation independently of the ubiquitin-proteasome pathway | Oryctolagus cuniculus | ? | - |
? |