Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.53 extracted from

  • Smith, S.D.; Jia, Z.; Huynh, K.K.; Wells, A.; Elce, J.S.
    Glutamate substitutions at a PKA consensus site are consistent with inactivation of calpain by phosphorylation (2003), FEBS Lett., 542, 115-118.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
S369D inactive mutant enzyme Rattus norvegicus
S50D mutant enzyme has the same specific activity and Ca2+ requirement as the wild-type enzyme Rattus norvegicus
S50E mutant enzyme has the same specific activity and Ca2+ requirement as the wild-type enzyme Rattus norvegicus
S67E mutant enzyme has the same specific activity and Ca2+ requirement as the wild-type enzyme Rattus norvegicus
T370E inactive mutant enzyme Rattus norvegicus
T70E mutant enzyme has the same specific activity and Ca2+ requirement as the wild-type enzyme Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ wild-type enzyme has a Kd-value of 0.325 mM Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-