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Literature summary for 3.4.22.52 extracted from

  • Van Ba, H.; Inho, H.
    Significant role of mu-calpain (CANP1) in proliferation/survival of bovine skeletal muscle satellite cells (2013), In Vitro Cell. Dev. Biol. Anim., 49, 785-797.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.52

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
skeletal muscle satellite cell
-
 Bos taurus
-

Synonyms

Synonyms Comment Organism
CANP1
-
 Bos taurus
mu-calpain
-
 Bos taurus

General Information

General Information Comment Organism
malfunction suppression of calpain 1 significantly reduces cell viability in cell proliferation when compared with control cells. Suppression of calpain 1 results in an increase in the expressions of apoptotic caspases such as caspase-3, caspase-6, caspase-7, caspase-8, and caspase-9, as well as heat-shock protein systems and leads to the upregulation of other apoptosis and DNA damage-regulating genes whilst at the same time downregulating proliferation, migration, and differentiation-regulating genes Bos taurus
physiological function the enzyme plays key roles in regulation of cell proliferation and survival of of bovine skeletal satellite cells Bos taurus