Literature summary for 3.4.22.52 extracted from

Zadran, S.; Jourdi, H.; Rostamiani, K.; Qin, Q.; Bi, X.; Baudry, M.
Brain-derived neurotrophic factor and epidermal growth factor activate neuronal m-calpain via mitogen-activated protein kinase-dependent phosphorylation (2010), J. Neurosci., 30, 1086-1095.

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Metals/Ions

Metals/Ions	Comment	Organism	Structure
Ca2+	the enzyme requires micromolar calcium concentrations for activation	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	brain-derived neurotrophic factor does not stimulate mu-calpain serine phosphorylation	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
HEK-TrkB cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
calpain1	-	Homo sapiens
mu-calpain	-	Homo sapiens

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Release 2023.1 (January 2023)