Inhibitors | Comment | Organism | Structure |
---|---|---|---|
acetyl-Leu-Leu-Nle-CHO | - |
Rattus norvegicus | |
calpain inhibitor III | - |
Rattus norvegicus | |
calpain inhibitor VI | - |
Rattus norvegicus | |
calpeptin | - |
Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-spectrin + H2O | Rattus norvegicus | - |
? | - |
? | |
Na+/Ca2+ exchanger isoform 3 + H2O | Rattus norvegicus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hippocampus | - |
Rattus norvegicus | - |
neuron | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-spectrin + H2O | - |
Rattus norvegicus | ? | - |
? | |
Na+/Ca2+ exchanger isoform 3 + H2O | - |
Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
calpain 1 | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0000075 | - |
pH and temperature not specified in the publication | Rattus norvegicus | calpain inhibitor VI | |
0.000008 | - |
pH and temperature not specified in the publication | Rattus norvegicus | calpain inhibitor III | |
0.000052 | - |
pH and temperature not specified in the publication | Rattus norvegicus | calpeptin | |
0.00019 | - |
pH and temperature not specified in the publication | Rattus norvegicus | acetyl-Leu-Leu-Nle-CHO |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | MK801 added shortly after glutamate prevents calpain 1 activation | down |
Rattus norvegicus | delayed calcium deregulation is not sufficient to activate calpain 1 | additional information |