Inhibitors | Comment | Organism | Structure |
---|---|---|---|
calpain inhibitor 1 | synthetic calpain inhibitor | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
neuronal nitric oxide synthase + H2O | Homo sapiens | the mechanism of neuronal nitric oxide synthase activation is promoted by a calpain-mediated limited proteolysis through conversion of native 160 kDa nNOS into a fully active 130 kDa | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
neuronal nitric oxide synthase + H2O | the mechanism of neuronal nitric oxide synthase activation is promoted by a calpain-mediated limited proteolysis through conversion of native 160 kDa nNOS into a fully active 130 kDa | Homo sapiens | ? | - |
? | |
tert-butyloxycarbonyl-Leu-Met-7-amido-4-chloromethylcoumarin + H2O | - |
Homo sapiens | tert-butyloxycarbonyl-Leu-Met + 7-amino-4-chloromethylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
mu-calpain | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | mu-calpain is specifically recruited into the NMDA receptor-neuronal nitric oxide synthase-heat shock protein 90 complex following calcium loading | Homo sapiens |