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Literature summary for 3.4.22.52 extracted from
- Regulation of podoplanin/PA2.26 antigen expression in tumour cells. Involvement of calpain-mediated proteolysis (2009), Int. J. Biochem. Cell Biol., 41, 1421-1429.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| calpeptin | - |
Homo sapiens |  |
| N-acetyl-Leu-Leu-Norleu-al | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HaCaT cell | - |
Homo sapiens | - |
| HEK-293T cell | - |
Homo sapiens | - |
| HeLa cell | - |
Homo sapiens | - |
| HN-30 cell | - |
Homo sapiens | - |
| HT-1080 cell | - |
Homo sapiens | - |
| KLE cell | - |
Homo sapiens | - |
| NCCIT cell | - |
Homo sapiens | - |
| NTERA-2 cell | - |
Homo sapiens | - |
| SCC-13 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| podoplanin + H2O | podoplanin stability is post-translationally regulated by calpain-1 | Homo sapiens | ? | - |
? | |
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