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Literature summary for 3.4.22.52 extracted from

  • Ozaki, T.; Yamashita, T.; Ishiguro, S.
    Mitochondrial m-calpain plays a role in the release of truncated apoptosis-inducing factor from the mitochondria (2009), Biochim. Biophys. Acta, 1793, 1848-1859.
    View publication on PubMed
Search for more literature for 3.4.22.52

Inhibitors

Inhibitors Comment Organism Structure
calpastatin
-
 Rattus norvegicus
PD150606
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ micromolar (0.005-0.05 mM) Ca2+ concentrations are required for activation in vitro Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 1 * 80000 + 1 * 30000, SDS-PAGE Rattus norvegicus
80000
-
 1 * 80000 + 1 * 30000, SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
apoptosis-inducing factor + H2O Rattus norvegicus
-
 truncated apoptosis-inducing factor + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
apoptosis-inducing factor + H2O
-
 Rattus norvegicus truncated apoptosis-inducing factor + ?
-
 ?

Subunits

Subunits Comment Organism
heterodimer 1 * 80000 + 1 * 30000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
mu-calpain
-
 Rattus norvegicus