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Literature summary for 3.4.22.52 extracted from

  • Sun, M.; Zhao, Y.; Gu, Y.; Xu, C.
    Inhibition of nNOS reduces ischemic cell death through down-regulating calpain and caspase-3 after experimental stroke (2009), Neurochem. Int., 54, 339-346.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-spectrin + H2O Rattus norvegicus
-
?
-
?
MAP2 + H2O Rattus norvegicus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain penumbra Rattus norvegicus
-
brain cortex
-
Rattus norvegicus
-
corpus striatum
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-spectrin + H2O
-
Rattus norvegicus ?
-
?
casein + H2O
-
Rattus norvegicus ?
-
?
MAP2 + H2O
-
Rattus norvegicus ?
-
?

Synonyms

Synonyms Comment Organism
mu-calpain
-
Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus treatment with 50 mg/kg 7-nitroindozale shows significant suppression of the activity of mu-calpain in brain cortex (penumbra), however, it has no significant effect on the mu-calpain activity in core (striatum and overlying cortex) down