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Literature summary for 3.4.22.52 extracted from
- Calpain 1 binding capacities of the N1-line region of titin are significantly enhanced by physiological concentrations of calcium (2008), Biochemistry, 47, 9174-9183.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| intracellular | - |
Sus scrofa | 5622 | - |
| intracellular | - |
Bos taurus | 5622 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | calcium-dependent, increase of amount of bound calpain 1 by calcium binding to titin | Sus scrofa |  |
| Ca2+ | calcium-dependent, increase of amount of bound calpain 1 by calcium binding to titin | Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Sus scrofa | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| skeletal muscle | musculus sternomandibularis | Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| titin + H2O | pH 7.5, absence or presence of 12 microM calcium | Sus scrofa | ? | - |
? | |
| titin + H2O | pH 7.5, absence or presence of 12 microM calcium | Bos taurus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| heterodimer | - |
Sus scrofa |
| heterodimer | - |
Bos taurus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| calpain 1 | - |
Sus scrofa |
| calpain 1 | - |
Bos taurus |
| micro-calpain | - |
Sus scrofa |
| micro-calpain | - |
Bos taurus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Sus scrofa |
| 7.5 | - |
- |
Bos taurus |
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Release 2023.1 (January 2023)
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