Literature summary for 3.4.22.52 extracted from

  • Sha, D.; Jin, Y.; Wu, H.; Wei, J.; Lin, C.H.; Lee, Y.H.; Buddhala, C.; Kuchay, S.; Chishti, A.H.; Wu, J.Y.
    Role of mu-calpain in proteolytic cleavage of brain L-glutamic acid decarboxylase (2008), Brain Res., 1207C, 9-18.
    View publication on PubMedView publication on EuropePMC

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ mu-calpain is activated by neuronal stimulation and Ca2+-influx Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
full-length glutamic acid decraboxylase67 + H2O Mus musculus in mu-calpain knockout mice, the level of truncated glutamic acid decarboxylase67 in the brain is greatly reduced compared with the wild-type. mu-Calpain is activated by neuronal stimulation and Ca2+-influx truncated glutamic acid decarboxylase67 + ?
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?

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
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Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
full-length glutamic acid decraboxylase67 + H2O
-
Mus musculus truncated glutamic acid decarboxylase67 + ?
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?
full-length glutamic acid decraboxylase67 + H2O in mu-calpain knockout mice, the level of truncated glutamic acid decarboxylase67 in the brain is greatly reduced compared with the wild-type. mu-Calpain is activated by neuronal stimulation and Ca2+-influx Mus musculus truncated glutamic acid decarboxylase67 + ?
-
?

Synonyms

Synonyms Comment Organism
mu-calpain
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Mus musculus