Literature summary for 3.4.22.52 extracted from

  • Kulkarni, S.; Goll, D.E.; Fox, J.E.B.
    Calpain cleaves RhoA generating a dominant-negative form that inhibits integrin-induced actin filament assembly and cell spreading (2002), J. Biol. Chem., 277, 24435-24441.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
RhoA + H2O Bos taurus calpain cleaves RhoA and generates a form that inhibits integrin-induced stress fiber assembly and cell spreading ?
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
skeletal muscle
-
Bos taurus
-
endothelial cell from aorta Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
RhoA + H2O
-
Bos taurus ?
-
?
RhoA + H2O calpain cleaves RhoA and generates a form that inhibits integrin-induced stress fiber assembly and cell spreading Bos taurus ?
-
?