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Literature summary for 3.4.22.14 extracted from

  • Grozdanovic, M.M.; Ostojic, S.; Aleksic, I.; Andjelkovic, U.; Petersen, A.; Gavrovic-Jankulovic, M.
    Active actinidin retains function upon gastro-intestinal digestion and is more thermostable than the E-64-inhibited counterpart (2014), J. Sci. Food Agric., 94, 3046-3052.
    View publication on PubMed

General Stability

General Stability Organism
active actinidin retains its primary structure and proteolytic activity after 2 h of simulated gastric digestion, followed by 2 h of intestinal digestion Actinidia deliciosa

Inhibitors

Inhibitors Comment Organism Structure
N-(trans-epoxysuccinyl)-L-leucine 4-guanidinobutylamide in contrast to actinidin without inhibitor, the actinidin–E-64 complex starts degrading 15 min after incubation in simulated gastric fluid (SGF) and is fully degraded after 60 min of incubation. In addition transition maximum temperature (Tm) of the actinidin-inhibitor complex is 61°C in contrast to Tm: 73.9° of actinidin without inhibitor Actinidia deliciosa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
23880
-
MALDI-TOF Actinidia deliciosa

Organism

Organism UniProt Comment Textmining
Actinidia deliciosa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Synonyms

Synonyms Comment Organism
actinidin
-
Actinidia deliciosa

General Information

General Information Comment Organism
metabolism active actinidin retains its primary structure and proteolytic activity after 2 h of simulated gastric digestion, followed by 2 h of intestinal digestion Actinidia deliciosa