Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus pyogenes | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
casein + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
E-cadherin + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
occludin + H2O | - |
Streptococcus pyogenes | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SpeB | - |
Streptococcus pyogenes |
streptococcal pyrogenic exotoxin B | - |
Streptococcus pyogenes |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Streptococcus pyogenes |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.6 | - |
assay at | Streptococcus pyogenes |
General Information | Comment | Organism |
---|---|---|
malfunction | wild type strain efficiently translocates across the epithelial monolayer along with cleavage of occludin and E-cadherin. Deletion of the speB gene compromises those activities. Destabilization of the junctional proteins is relieved in cells infected with the speB mutant, as compared with those infected with the wild type | Streptococcus pyogenes |