Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
160000 | - |
gel filtration | Streptococcus pyogenes |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
human CXCL-1 + H2O | Streptococcus pyogenes | the cleavage site is between lysine residues K60 and K61 | ? | - |
? | |
human CXCL-1 + H2O | Streptococcus pyogenes H292 | the cleavage site is between lysine residues K60 and K61 | ? | - |
? | |
human CXCL-2 + H2O | Streptococcus pyogenes | the cleavage site is between lysine residues K60 and K61 | ? | - |
? | |
human CXCL-2 + H2O | Streptococcus pyogenes H292 | the cleavage site is between lysine residues K60 and K61 | ? | - |
? | |
human CXCL-6 + H2O | Streptococcus pyogenes | - |
? | - |
? | |
human CXCL-6 + H2O | Streptococcus pyogenes H292 | - |
? | - |
? | |
human CXCL-8 + H2O | Streptococcus pyogenes | - |
? | - |
? | |
human CXCL-8 + H2O | Streptococcus pyogenes H292 | - |
? | - |
? | |
mouse CXCL-1 + H2O | Streptococcus pyogenes | the cleavage site is between lysine residues K65 and K66 | ? | - |
? | |
mouse CXCL-1 + H2O | Streptococcus pyogenes H292 | the cleavage site is between lysine residues K65 and K66 | ? | - |
? | |
mouse CXCL-2 + H2O | Streptococcus pyogenes | the cleavage site is between lysine residues K65 and K66 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus pyogenes | - |
- |
- |
Streptococcus pyogenes H292 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
human CXCL-1 + H2O | the cleavage site is between lysine residues K60 and K61 | Streptococcus pyogenes | ? | - |
? | |
human CXCL-1 + H2O | the cleavage site is between lysine residues K60 and K61 | Streptococcus pyogenes H292 | ? | - |
? | |
human CXCL-2 + H2O | the cleavage site is between lysine residues K60 and K61 | Streptococcus pyogenes | ? | - |
? | |
human CXCL-2 + H2O | the cleavage site is between lysine residues K60 and K61 | Streptococcus pyogenes H292 | ? | - |
? | |
human CXCL-6 + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
human CXCL-6 + H2O | - |
Streptococcus pyogenes H292 | ? | - |
? | |
human CXCL-8 + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
human CXCL-8 + H2O | - |
Streptococcus pyogenes H292 | ? | - |
? | |
mouse CXCL-1 + H2O | the cleavage site is between lysine residues K65 and K66 | Streptococcus pyogenes | ? | - |
? | |
mouse CXCL-1 + H2O | the cleavage site is between lysine residues K65 and K66 | Streptococcus pyogenes H292 | ? | - |
? | |
mouse CXCL-2 + H2O | the cleavage site is between lysine residues K65 and K66 | Streptococcus pyogenes | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SpcCEP | - |
Streptococcus pyogenes |
General Information | Comment | Organism |
---|---|---|
physiological function | in infected mice, SpyCEP expression by Streptococcus pyogenes hinders bacterial clearance from muscle, and enhances bacterial spread, associated with cleavage of CXCL1. SpyCEP is necessary and sufficient for bacterial dissemination within soft tissues. SpyCEP enhances Streptococcus pyogenes dissemination to lower respiratory tract from nasopharynx | Streptococcus pyogenes |