Any feedback?
Literature summary for 3.4.22.10 extracted from
- Degradation of complement 3 by streptococcal pyrogenic exotoxin B inhibits complement activation and neutrophil opsonophagocytosis (2008), Infect. Immun., 76, 1163-1169.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) cells | Streptococcus pyogenes |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| C192S | lacks protease activity | Streptococcus pyogenes |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 28000 | - |
active mature enzyme, SDS-PAGE | Streptococcus pyogenes |
| 40000 | - |
inactive pro-enzyme, SDS-PAGE | Streptococcus pyogenes |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptococcus pyogenes | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni2+-chelating column chromatography | Streptococcus pyogenes |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| complement component C3 + H2O | - |
Streptococcus pyogenes | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Spe B | - |
Streptococcus pyogenes |
| streptococcal pyrogenic exotoxin B | - |
Streptococcus pyogenes |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
